Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
EHI73993.1L-2-hydroxyisocaproate dehydrogenase; Belongs to the LDH/MDH superfamily. (296 aa)    
Predicted Functional Partners:
EHI74307.1
Putative pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.918
EHI73948.1
Hypothetical protein.
  
 0.872
icd
Isocitrate dehydrogenase.
  
 0.856
acoB
TPP-dependent acetoin dehydrogenase complex, E1 component, beta subunit.
   
 0.845
pgi
Putative Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 0.836
EHI74774.1
Putative aminotransferase AlaT.
  
 0.830
gapN
Glyceraldehyde-3-phosphate dehydrogenase (NADP+); Belongs to the aldehyde dehydrogenase family.
   
 0.796
EHI74433.1
Putative NAD-dependent malic enzyme 3.
  
 0.774
EHI74560.1
Fructose-6-phosphate aldolase.
   
 0.766
EHI74687.1
Putative TPP-dependent acetoin dehydrogenase complex, E3 component, dihydrolipoyl dehydrogenase.
  
 0.764
Your Current Organism:
Streptococcus criceti
NCBI taxonomy Id: 873449
Other names: S. criceti HS-6, Streptococcus criceti HS-6, Streptococcus criceti str. HS-6, Streptococcus criceti strain HS-6
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