| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EHI73409.1 | EHI73887.1 | STRCR_1386 | STRCR_1385 | Hypothetical protein; Identified by glimmer; putative. | hydroxymethylglutaryl-CoA synthase. | 0.620 |
| EHI73409.1 | EHI74748.1 | STRCR_1386 | STRCR_1388 | Hypothetical protein; Identified by glimmer; putative. | Dihydrofolate reductase family protein; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 0.406 |
| EHI73409.1 | EHI75027.1 | STRCR_1386 | STRCR_1384 | Hypothetical protein; Identified by glimmer; putative. | Polysaccharide deacetylase family protein. | 0.620 |
| EHI73409.1 | thyA | STRCR_1386 | STRCR_1387 | Hypothetical protein; Identified by glimmer; putative. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.556 |
| EHI73887.1 | EHI73409.1 | STRCR_1385 | STRCR_1386 | hydroxymethylglutaryl-CoA synthase. | Hypothetical protein; Identified by glimmer; putative. | 0.620 |
| EHI73887.1 | EHI74748.1 | STRCR_1385 | STRCR_1388 | hydroxymethylglutaryl-CoA synthase. | Dihydrofolate reductase family protein; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 0.625 |
| EHI73887.1 | EHI75027.1 | STRCR_1385 | STRCR_1384 | hydroxymethylglutaryl-CoA synthase. | Polysaccharide deacetylase family protein. | 0.799 |
| EHI73887.1 | thyA | STRCR_1385 | STRCR_1387 | hydroxymethylglutaryl-CoA synthase. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.690 |
| EHI74748.1 | EHI73409.1 | STRCR_1388 | STRCR_1386 | Dihydrofolate reductase family protein; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Hypothetical protein; Identified by glimmer; putative. | 0.406 |
| EHI74748.1 | EHI73887.1 | STRCR_1388 | STRCR_1385 | Dihydrofolate reductase family protein; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | hydroxymethylglutaryl-CoA synthase. | 0.625 |
| EHI74748.1 | thyA | STRCR_1388 | STRCR_1387 | Dihydrofolate reductase family protein; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.999 |
| EHI75027.1 | EHI73409.1 | STRCR_1384 | STRCR_1386 | Polysaccharide deacetylase family protein. | Hypothetical protein; Identified by glimmer; putative. | 0.620 |
| EHI75027.1 | EHI73887.1 | STRCR_1384 | STRCR_1385 | Polysaccharide deacetylase family protein. | hydroxymethylglutaryl-CoA synthase. | 0.799 |
| EHI75027.1 | thyA | STRCR_1384 | STRCR_1387 | Polysaccharide deacetylase family protein. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.455 |
| thyA | EHI73409.1 | STRCR_1387 | STRCR_1386 | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | Hypothetical protein; Identified by glimmer; putative. | 0.556 |
| thyA | EHI73887.1 | STRCR_1387 | STRCR_1385 | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | hydroxymethylglutaryl-CoA synthase. | 0.690 |
| thyA | EHI74748.1 | STRCR_1387 | STRCR_1388 | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | Dihydrofolate reductase family protein; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 0.999 |
| thyA | EHI75027.1 | STRCR_1387 | STRCR_1384 | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | Polysaccharide deacetylase family protein. | 0.455 |