Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
dkgA2,5-diketo-D-gluconic acid reductase A; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop. (152 aa)    
Predicted Functional Partners:
EHI74769.1
Hypothetical protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop.
     0.990
EHI74688.1
Alcohol dehydrogenase, iron-dependent; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 0.751
EHI74107.1
Alcohol dehydrogenase, zinc-dependent.
  
  0.735
EHI73369.1
Hypothetical protein.
  
    0.711
EHI73999.1
Glyoxalase family protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.
   
  0.520
EHI73347.1
Hypothetical protein.
   
  0.520
gloA
Lactoylglutathione lyase.
   
  0.520
EHI74062.1
Hypothetical protein.
    
  0.483
EHI74520.1
3-oxoacyl-[acyl-carrier-protein] reductase family protein.
  
  0.468
EHI74444.1
Putative glyoxylate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
  0.452
Your Current Organism:
Streptococcus criceti
NCBI taxonomy Id: 873449
Other names: S. criceti HS-6, Streptococcus criceti HS-6, Streptococcus criceti str. HS-6, Streptococcus criceti strain HS-6
Server load: low (40%) [HD]