Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EHI73911.1RelA/SpoT domain protein. (205 aa)    
Predicted Functional Partners:
EHI75084.1
Putative bifunctional (P)ppGpp synthase/hydrolase RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
     
 0.961
EHI74581.1
Sensor histidine kinase.
 
  
  0.959
awd
Nucleoside pyrophosphate kinase.
     
  0.953
EHI75265.1
GTP pyrophosphokinase family protein.
  
  
 
0.931
EHI74159.1
DNA-binding response regulator.
  
  0.927
nrdD
Anaerobic ribonucleoside-triphosphate reductase.
     
  0.911
folE
GTP cyclohydrolase 1.
     
  0.911
mnmE
Putative tRNA modification GTPase MnmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
  
    0.610
EHI74926.1
NIF3 family protein.
     
  0.596
EHI75489.1
Hypothetical protein.
       0.553
Your Current Organism:
Streptococcus criceti
NCBI taxonomy Id: 873449
Other names: S. criceti HS-6, Streptococcus criceti HS-6, Streptococcus criceti str. HS-6, Streptococcus criceti strain HS-6
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