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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyrKDihydroorotate dehydrogenase, electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). (264 aa)    
Predicted Functional Partners:
pyrD-2
Dihydroorotate dehydrogenase 1B; Catalyzes the conversion of dihydroorotate to orotate.
 
 0.998
pyrC
Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
 
 
 0.989
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
 
 0.986
pyrD
Dihydroorotate dehydrogenase 1A; Catalyzes the conversion of dihydroorotate to orotate.
 
 0.978
carB
Carbamoyl phosphate synthase large subunit; Belongs to the CarB family.
  
 0.976
pyrF
Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
 
 
 0.974
carA
Carbamoyl phosphate synthase small subunit; Belongs to the CarA family.
  
 
 0.971
pyrB
Putative aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
 
 
 0.969
EHI74688.1
Alcohol dehydrogenase, iron-dependent; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 
 0.931
EHI73948.1
Hypothetical protein.
  
 0.918
Your Current Organism:
Streptococcus criceti
NCBI taxonomy Id: 873449
Other names: S. criceti HS-6, Streptococcus criceti HS-6, Streptococcus criceti str. HS-6, Streptococcus criceti strain HS-6
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