Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EHI75535.1Hydrolase, haloacid dehalogenase-like family protein. (198 aa)    
Predicted Functional Partners:
gyrB
DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
       0.846
EHI73737.1
Cell division protein, FtsW/RodA/SpoVE family; Belongs to the SEDS family.
       0.750
ezrA
Putative septation ring formation regulator EzrA; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family.
 
     0.725
EHI75160.1
Putative PTS system glucose-specific EIICBA component.
  
 
  0.723
EHI73579.1
PTS system, trehalose-specific IIBCA component.
  
 
  0.723
scrA
PTS system, sucrose-specific, EIIBCA component.
  
 
  0.723
bglP
PTS system beta-glucoside-specific EIIBCA component.
  
 
  0.723
EHI73643.1
PTS system, beta-glucoside-specific, IIABC component.
  
 
  0.723
EHI75087.1
PTS system, beta-glucoside-specific, IIABC component.
  
 
  0.723
EHI74912.1
Putative PTS system beta-glucoside-specific EIIBCA component.
  
 
  0.723
Your Current Organism:
Streptococcus criceti
NCBI taxonomy Id: 873449
Other names: S. criceti HS-6, Streptococcus criceti HS-6, Streptococcus criceti str. HS-6, Streptococcus criceti strain HS-6
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