Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EHI74433.1Putative NAD-dependent malic enzyme 3. (540 aa)    
Predicted Functional Partners:
EHI74307.1
Putative pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.950
EHI74229.1
Putative membrane protein.
 
  
 0.950
EHI74130.1
Citrate-sodium symporter family protein.
 
  
 0.941
acoB
TPP-dependent acetoin dehydrogenase complex, E1 component, beta subunit.
   
 
 0.931
EHI74406.1
Acetoin dehydrogenase, thymine PPi dependent, E1 component, alpha subunit.
   
 
 0.923
EHI74774.1
Putative aminotransferase AlaT.
  
 0.922
oadB
Sodium ion-translocating decarboxylase, beta subunit; Tunnel subunit of the primary sodium pump glutaconyl-CoA decarboxylase (GCD).
    
 0.919
EHI73947.1
Putative formate C-acetyltransferase.
   
 
 0.917
pycB
Pyruvate carboxylase subunit B.
     
 0.915
EHI74687.1
Putative TPP-dependent acetoin dehydrogenase complex, E3 component, dihydrolipoyl dehydrogenase.
  
 
 0.890
Your Current Organism:
Streptococcus criceti
NCBI taxonomy Id: 873449
Other names: S. criceti HS-6, Streptococcus criceti HS-6, Streptococcus criceti str. HS-6, Streptococcus criceti strain HS-6
Server load: medium (58%) [HD]