Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EHI73931.1Cystathionine gamma-synthase. (364 aa)    
Predicted Functional Partners:
EHI75284.1
Bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein.
  
 0.998
EHI73315.1
Aminotransferase, class II.
 
 
 0.991
EHI75068.1
Putative cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 0.989
metE
5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
  
 
 0.989
metAA
Putative homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.
  
 
 0.987
EHI73936.1
Homoserine dehydrogenase family protein.
  
 
 0.949
cysE
Serine O-acetyltransferase.
  
 
 0.947
EHI73515.1
Putative O-acetylhomoserine aminocarboxypropyltransferase.
 
 
0.944
ilvE
Branched-chain-amino-acid transaminase.
   
 0.936
ilvA
Threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
  
 
 0.934
Your Current Organism:
Streptococcus criceti
NCBI taxonomy Id: 873449
Other names: S. criceti HS-6, Streptococcus criceti HS-6, Streptococcus criceti str. HS-6, Streptococcus criceti strain HS-6
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