Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EHI74190.1Hypothetical protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift. (216 aa)    
Predicted Functional Partners:
EHI73424.1
Hypothetical protein.
 
  
 0.447
EHI74697.1
Iron-dependent transcriptional regulator.
       0.445
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
     
  0.426
hisC
Putative histidinol-phosphate transaminase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
     
  0.426
EHI73344.1
Histidinol phosphate phosphatase HisJ family protein; Belongs to the PHP hydrolase family. HisK subfamily.
     
  0.426
fhuB
Ferrichrome ABC transporter, permease protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
       0.413
EHI75057.1
Iron compound ABC transporter, permease protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
       0.413
EHI73706.1
Hypothetical protein.
  
    0.407
Your Current Organism:
Streptococcus criceti
NCBI taxonomy Id: 873449
Other names: S. criceti HS-6, Streptococcus criceti HS-6, Streptococcus criceti str. HS-6, Streptococcus criceti strain HS-6
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