Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cysKCysteine synthase A; COG: COG0031; Pfam: PF00291; InterPro: IPR005859; Belongs to the cysteine synthase/cystathionine beta- synthase family. (315 aa)    
Predicted Functional Partners:
cysE
Putative serine O-acetyltransferase; COG: COG1045; Pfam: PF00132.
 
 0.996
EFU29312.1
Pyridine nucleotide-disulfide oxidoreductase; COG: COG0446; Pfam: PF07992,PF00070,PF02852,PF00581,PF01206; InterPro: IPR013027; Belongs to the sulfur carrier protein TusA family.
  
 
 0.960
cysS
cysteine--tRNA ligase; COG: COG0215; Pfam: PF01406,PF09190; InterPro: IPR002308; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 0.910
luxS
S-ribosylhomocysteinase LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
  
 
 0.909
metH-2
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
 0.907
serC
Phosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
    
 0.882
EFU31917.1
Aminotransferase, class I/II; COG: COG1168; Pfam: PF00155; InterPro: IPR004839.
    
 0.873
coaBC
Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; COG: COG0452; Pfam: PF02441,PF04127; InterPro: IPR005252.
    
  0.864
aspC
Aminotransferase, class I/II; COG: COG0436; Pfam: PF00155; InterPro: IPR004839.
     
 0.863
aspC2
Aminotransferase, class I/II; COG: COG0436; Pfam: PF00155; InterPro: IPR004839.
     
 0.863
Your Current Organism:
Prevotella buccae
NCBI taxonomy Id: 873513
Other names: P. buccae ATCC 33574, Prevotella buccae ATCC 33574, Prevotella buccae CIP 105106, Prevotella buccae str. ATCC 33574, Prevotella buccae strain ATCC 33574
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