STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Cooccurrence
Coexpression
Experiments
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[Homology]
Score
aroEPutative shikimate dehydrogenase; COG: COG0169; Pfam: PF08501,PF01488; InterPro: IPR016040. (263 aa)    
Predicted Functional Partners:
aroA
Putative 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
 
 0.993
aroB
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
 
 0.987
aroK
Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
 
 
 0.982
aroQ
3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.
 
 
 0.962
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
 0.962
pheB
Putative 3-deoxy-7-phosphoheptulonate synthase; COG: COG2876; Pfam: PF00793,PF01817; InterPro: IPR013785.
 
 
 0.950
EFU30047.1
Hypothetical protein; COG: COG0150; Pfam: PF02769.
     
 0.851
panD
Glutamine amidotransferase, class I; COG: COG0512; Pfam: PF00117; InterPro: IPR006221.
 
 0.835
ubiE
Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
 
  
 0.827
EFU30043.1
PhoH family protein; COG: COG1702; Pfam: PF02562; InterPro: IPR003714.
       0.769
Your Current Organism:
Prevotella buccae
NCBI taxonomy Id: 873513
Other names: P. buccae ATCC 33574, Prevotella buccae ATCC 33574, Prevotella buccae CIP 105106, Prevotella buccae str. ATCC 33574, Prevotella buccae strain ATCC 33574
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