Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
EFU30047.1Hypothetical protein; COG: COG0150; Pfam: PF02769. (405 aa)    
Predicted Functional Partners:
purL
Putative phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
 
 
 0.999
purC-2
Phosphoribosylaminoimidazolesuccinocarboxamide synthase; COG: COG0152; Pfam: PF01259; InterPro: IPR001636; Belongs to the SAICAR synthetase family.
 
 0.999
purB
Adenylosuccinate lyase; COG: COG0015; Pfam: PF00206,PF08328; InterPro: IPR004769; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
 
 
 0.991
purD
Phosphoribosylamine--glycine ligase; COG: COG0151; Pfam: PF02844,PF01071,PF02843; InterPro: IPR000115; Belongs to the GARS family.
 
 
 0.975
purF
Class II glutamine amidotransferase; COG: COG0034; Pfam: PF00310,PF02906; InterPro: IPR005854.
 
 
 0.968
purE
Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
 
 
 0.959
purN
Putative phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
 
  
 0.952
purT
Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family.
  
 
 0.901
purF2
Putative amidophosphoribosyltransferase; COG: COG0034; Pfam: PF00156; InterPro: IPR005854; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
 
 0.859
purH
MGS-like domain protein; COG: COG0138; Pfam: PF02142,PF01808; InterPro: IPR002695.
 
  
 0.856
Your Current Organism:
Prevotella buccae
NCBI taxonomy Id: 873513
Other names: P. buccae ATCC 33574, Prevotella buccae ATCC 33574, Prevotella buccae CIP 105106, Prevotella buccae str. ATCC 33574, Prevotella buccae strain ATCC 33574
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