Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EFU30056.1Tetratricopeptide repeat protein; COG: COG0507; Pfam: PF07719. (563 aa)    
Predicted Functional Partners:
pcrA
UvrD/REP helicase; COG: COG0210; Pfam: PF00580; InterPro: IPR000212.
   
 0.754
recQ
ATP-dependent DNA helicase RecQ; COG: COG0514; Pfam: PF00270,PF00271,PF00570; InterPro: IPR004589.
    
   0.750
recQ2
ATP-dependent DNA helicase, RecQ family; COG: COG0514; Pfam: PF00270,PF00271; InterPro: IPR004589.
    
   0.750
EFU32023.1
Tetratricopeptide repeat protein; InterPro: IPR011990.
  
 0.700
EFU30055.1
Transglycosylase; COG: COG5009; Pfam: PF00912,PF00905; InterPro: IPR001460.
       0.672
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 0.650
dnaN
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 0.634
miaA
tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.
  
  
 0.634
EFU29864.1
Gram-positive signal peptide protein, YSIRK family.
    
  0.613
htpG
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; COG: COG0326; Pfam: PF02518,PF00183; InterPro: IPR001404.
   
 0.604
Your Current Organism:
Prevotella buccae
NCBI taxonomy Id: 873513
Other names: P. buccae ATCC 33574, Prevotella buccae ATCC 33574, Prevotella buccae CIP 105106, Prevotella buccae str. ATCC 33574, Prevotella buccae strain ATCC 33574
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