Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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yjcEIntegral membrane transport protein; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (535 aa)    
Predicted Functional Partners:
AEF34365.1
Conserved hypothetical protein.
       0.651
purT
Formate-dependent phosphoribosylglycinamide formyltransferase PurT; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate. Belongs to the PurK/PurT family.
       0.569
AEF38114.1
Putative Na+/H+ antiporter protein.
  
 
 0.562
metH
5-methyltetrahydrofolate--homocysteine methyltransferase MetH; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
 0.557
AEF34914.1
NADH ubiquinone oxidoreductase subunit 5.
     
 0.530
metZ
O-succinylhomoserine sulfhydrylase MetZ; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
  
  
 0.510
AEF37623.1
MCE-associated protein.
  
 
 0.509
comEA
Membrane protein ComEA.
      
 0.508
AEF34368.1
Conserved hypothetical protein.
       0.480
ctpE
Metal cation transporter ATPase p-type CtpE.
 
 
 
 0.448
Your Current Organism:
Mycolicibacter sinensis
NCBI taxonomy Id: 875328
Other names: M. sinensis, Mycobacterium sinense, Mycobacterium sinov, Mycobacterium sp. 506, Mycobacterium sp. JDM601, strain JDM601
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