STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dnaE2DNA polymerase III alpha chain DnaE2; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. (1094 aa)    
Predicted Functional Partners:
AEF37217.1
Conserved hypothetical protein.
 
  
 0.934
AEF37216.1
Conserved hypothetical protein.
 
  
 0.905
holA
DNA polymerase III delta subunit HolA.
  
 
 0.875
dnaN
DNA polymerase III (beta chain) DnaN; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiatio [...]
    
 
 0.848
dnaZX
DNA polymerase III (subunit gamma/tau) DnaZX; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
 
 
 0.836
dinP_1
DNA polymerase IV DinP_1; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
 
  
 0.810
AEF37929.1
DNA polymerase III subunit delta'.
  
 
 0.809
AEF35430.1
Single-stranded DNA-binding protein.
   
 
 0.799
ssb
Single-strand binding protein Ssb.
   
 
 0.799
AEF35711.1
Conserved hypothetical protein.
 
 
 0.699
Your Current Organism:
Mycolicibacter sinensis
NCBI taxonomy Id: 875328
Other names: M. sinensis, Mycobacterium sinense, Mycobacterium sinov, Mycobacterium sp. 506, Mycobacterium sp. JDM601, strain JDM601
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.