Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-expression
Experiments
Databases
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[Homology]
Score
AEF37208.1Conserved hypothetical protein. (290 aa)    
Predicted Functional Partners:
otsB2
Trehalose-6-phosphate phosphatase OtsB2; Removes the phosphate from trehalose 6-phosphate to produce free trehalose.
 
  
 0.701
AEF36293.1
Conserved hypothetical protein.
 
  
 0.584
pta
Phosphate acetyltransferase Pta; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
  
  
 0.556
AEF34438.1
Conserved hypothetical protein.
 
  
 0.505
AEF37050.1
Catalase HPII; Serves to protect cells from the toxic effects of hydrogen peroxide.
  
  
 0.481
ogt
methylated-DNA-protein-cysteine methyltransferase Ogt; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
  
  
 0.480
fadE25_2-2
acyl-CoA dehydrogenase FadE25_2.
       0.466
hpf
Conserved hypothetical protein; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.
  
  
 0.465
devR
Two-component transcriptional regulatory protein DevR.
  
  
 0.438
AEF37056.1
Conserved hypothetical protein.
  
  
 0.438
Your Current Organism:
Mycolicibacter sinensis
NCBI taxonomy Id: 875328
Other names: M. sinensis, Mycobacterium sinense, Mycobacterium sinov, Mycobacterium sp. 506, Mycobacterium sp. JDM601, strain JDM601
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