Automated, unsupervised textmining - searching for proteins that are frequently mentioned together.
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Fusion
Genes that are sometimes fused into single open reading frames.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
Node Content
empty nodes: proteins of unknown 3D structure
filled nodes: a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMB91934.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (457 aa)
Predicted Functional Partners:
AMB91933.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the uroporphyrinogen decarboxylase family.
0.894
Your Current Organism:
Aerococcus christensenii
NCBI taxonomy Id: 87541 Other names: A. christensenii, Aerococcus sp. CCUG 28826, CCUG 28831, CIP 106115, DSM 15819, strain UWO6
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
node1
node2
node1 accession
node2 accession
node1 annotation
node2 annotation
score
AMB91933.1
AMB91934.1
AWM71_00575
AWM71_00580
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the uroporphyrinogen decarboxylase family.
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
0.894
AMB91934.1
AMB91933.1
AWM71_00580
AWM71_00575
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the uroporphyrinogen decarboxylase family.
0.894
Network Stats
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Functional enrichments in your networkNote: some enrichments may be expected here (why?) disable highlightexplain columns
Enrichment analysis is still ongoing, please wait ...
Statistical background
For the above enrichment analysis, the following statistical background is assumed: