STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXI24628.1Ion channel; Derived by automated computational analysis using gene prediction method: Protein Homology. (234 aa)    
Predicted Functional Partners:
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
    
 
 0.781
KXI21854.1
Abortive phage infection protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.781
parE
DNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.
    
 
 0.781
KXI21589.1
N-acetylmuramoyl-L-alanine amidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.773
KXI24627.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.756
KXI24477.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.748
KXI24478.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
     
 0.748
KXI24445.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.722
KXI22406.1
Lytic transglycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.710
KXI21606.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.629
Your Current Organism:
Photobacterium sanguinicancri
NCBI taxonomy Id: 875932
Other names: CECT 7579, DSM 24670, P. sanguinicancri, Photobacterium sanguinicancri Gomez-Gil et al. 2016, Photobacterium sp. ME15, Photobacterium sp. Mj110, Photobacterium sp. Mj130, Photobacterium sp. Mj139, strain Mj110
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