STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RluA-2Pseudouridylate synthase for 23S rRNA; (position 746) and tRNAphe (position 32), dual specificity; COG0564 Pseudouridylate synthases, 23S RNA-specific. (209 aa)    
Predicted Functional Partners:
rapA
RNA polymerase associated protein (ATP-dependent helicase HepA); Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
  
   0.802
EAR29168.1
Hypothetical protein.
       0.727
rplX
50S ribosomal subunit protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
 
 
   0.521
rplU
50S ribosomal subunit protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
 
 
   0.519
EAR29369.1
Beta-ketoacyl synthase; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II.
   
 
 0.495
rsfS
Iojap domain protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
  
 
 0.480
mnmE
Predicted GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
   
 
 0.478
truD
tRNA pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family.
    
 
 0.478
obg
GTPase (Obg family) involved in ribosome maturation; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
 
 
 0.468
rplQ
COG0203 Ribosomal protein L17.
  
   0.460
Your Current Organism:
Pseudoalteromonas tunicata
NCBI taxonomy Id: 87626
Other names: P. tunicata D2, Pseudoalteromonas sp. D2, Pseudoalteromonas tunicata D2, Pseudoalteromonas tunicata str. D2, Pseudoalteromonas tunicata strain D2
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