STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BioF8-amino-7-oxononanoate synthase (7-keto-8-aminopelargonic acid synthetase); COG0156 7-keto-8-aminopelargonate synthetase and related enzymes. (378 aa)    
Predicted Functional Partners:
bioA
Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
 
 
 0.994
bioD
Desthiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.
 
  
 0.984
bioB
Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
  
 0.969
BioH
Putative enzyme in pimeloyl-CoA (biotin precursor) synthesis with alpha/beta-hydrolase domain; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).
 
 0.949
BioC
Desthiobiotin biosynthesis; COG0500 SAM-dependent methyltransferases.
  
  
 0.923
EAR29369.1
Beta-ketoacyl synthase; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II.
 
 
 0.839
EAR29352.1
Hypothetical protein; COG2091 Phosphopantetheinyl transferase; Belongs to the P-Pant transferase superfamily.
  
 
 0.739
tdh
L-threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family.
 
  
 0.687
EAR27078.1
Beta-ketoacyl synthase; COG0840 Methyl-accepting chemotaxis protein.
   
 
 0.533
htpX
Heat shock protein HtpX; COG0501 Zn-dependent protease with chaperone function; Belongs to the peptidase M48B family.
       0.507
Your Current Organism:
Pseudoalteromonas tunicata
NCBI taxonomy Id: 87626
Other names: P. tunicata D2, Pseudoalteromonas sp. D2, Pseudoalteromonas tunicata D2, Pseudoalteromonas tunicata str. D2, Pseudoalteromonas tunicata strain D2
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.