STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADZ08265.1KEGG: mmg:MTBMA_c01110 coenzyme F390 synthetase; TIGRFAM: Coenzyme F390 synthetase; PFAM: AMP-dependent synthetase/ligase. (446 aa)    
Predicted Functional Partners:
ADZ08667.1
Lactaldehyde dehydrogenase; KEGG: msi:Msm_0467 NADP-dependent glyceraldehyde-3-phosphate dehydrogenase; PFAM: Aldehyde dehydrogenase domain; Belongs to the aldehyde dehydrogenase family.
  
 
 0.795
ADZ09422.1
KEGG: mvn:Mevan_0177 serine O-acetyltransferase; TIGRFAM: Serine O-acetyltransferase.
     
 0.577
ADZ08266.1
PFAM: Haloacid dehalogenase-like hydrolase; KEGG: mth:MTH1793 hypothetical protein.
 
     0.561
ADZ09639.1
KEGG: mba:Mbar_A1645 phenylacetic acid degradation protein; TIGRFAM: Phenylacetic acid degradation-related protein; PFAM: Thioesterase superfamily.
 
  
 0.496
truD
tRNA pseudouridine synthase D; Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family.
  
    0.484
cofG
FO synthase subunit 1; Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) from 5-amino-5-(4-hydroxybenzyl)-6-(D- ribitylimino)-5,6-dihydrouracil.
     
 0.478
dadD
5-methylthioadenosine/S-adenosylhomocysteine deaminase; Catalyzes the deamination of three SAM-derived enzymatic products, namely 5'-deoxyadenosine, S-adenosyl-L-homocysteine, and 5'- methylthioadenosine, to produce the inosine analogs. Can also deaminate adenosine. The preferred substrate for this enzyme is 5'- deoxyadenosine, but all these substrates are efficiently deaminated. Likely functions in a S-adenosyl-L-methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions. May also be involved in the recycling of 5'- deoxya [...]
       0.455
ADZ09256.1
PFAM: Amino acid-binding ACT; KEGG: mth:MTH1854 hypothetical protein.
 
   0.430
ADZ08919.1
PFAM: Amino acid-binding ACT; KEGG: mmg:MTBMA_c04240 hypothetical protein.
 
   0.428
ADZ08269.1
Ureidoglycolate lyase; KEGG: mfv:Mfer_0698 5-carboxymethyl-2-hydroxymuconatedelta-isomerase; PFAM: Fumarylacetoacetase, C-terminal-like.
  
  
 0.408
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
Server load: medium (54%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.