close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADZ08269.1Ureidoglycolate lyase; KEGG: mfv:Mfer_0698 5-carboxymethyl-2-hydroxymuconatedelta-isomerase; PFAM: Fumarylacetoacetase, C-terminal-like. (259 aa)    
Predicted Functional Partners:
hisG
ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
  
    0.868
ADZ08667.1
Lactaldehyde dehydrogenase; KEGG: msi:Msm_0467 NADP-dependent glyceraldehyde-3-phosphate dehydrogenase; PFAM: Aldehyde dehydrogenase domain; Belongs to the aldehyde dehydrogenase family.
  
 
 0.753
dadD
5-methylthioadenosine/S-adenosylhomocysteine deaminase; Catalyzes the deamination of three SAM-derived enzymatic products, namely 5'-deoxyadenosine, S-adenosyl-L-homocysteine, and 5'- methylthioadenosine, to produce the inosine analogs. Can also deaminate adenosine. The preferred substrate for this enzyme is 5'- deoxyadenosine, but all these substrates are efficiently deaminated. Likely functions in a S-adenosyl-L-methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions. May also be involved in the recycling of 5'- deoxya [...]
   
 
 0.619
ADZ09848.1
Chloride peroxidase; KEGG: mpl:Mpal_2171 alpha/beta hydrolase fold protein; PFAM: Alpha/beta hydrolase fold-1.
  
  
 0.610
ADZ08266.1
PFAM: Haloacid dehalogenase-like hydrolase; KEGG: mth:MTH1793 hypothetical protein.
  
    0.555
ADZ08682.1
PFAM: Citrate synthase-like; KEGG: mmg:MTBMA_c13480 citrate synthase.
  
  
 0.543
ADZ08728.1
PFAM: Citrate synthase-like; KEGG: mmg:MTBMA_c03010 citrate synthase-related protein; Belongs to the citrate synthase family.
  
  
 0.543
ADZ09428.1
Cystathionine beta-lyase; KEGG: dly:Dehly_0142 class I and II aminotransferase; PFAM: Aminotransferase, class I/classII.
 
  
 0.458
ADZ08385.1
PFAM: Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B; KEGG: mpl:Mpal_2574 extradiol ring-cleavage dioxygenase class III protein subunit B.
  
  
 0.438
ADZ08558.1
KEGG: mru:mru_1987 pre-mRNA splicing ribonucleoprotein PRP31; PFAM: Pre-mRNA processing ribonucleoprotein, snoRNA-binding domain; NOSIC; SMART: NOSIC.
    
 0.438
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.