| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADZ08277.1 | ADZ08354.1 | Metbo_0024 | Metbo_0101 | PFAM: GTPase of unknown function C-terminal; GTP-binding protein, HSR1-related; TGS; KEGG: mth:MTH1515 translation-associated GTPase. | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. | 0.746 |
| ADZ08277.1 | argS | Metbo_0024 | Metbo_0089 | PFAM: GTPase of unknown function C-terminal; GTP-binding protein, HSR1-related; TGS; KEGG: mth:MTH1515 translation-associated GTPase. | KEGG: mth:MTH1447 arginyl-tRNA synthetase; TIGRFAM: Arginyl-tRNA synthetase, class Ic; HAMAP: Arginyl-tRNA synthetase, class Ic; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.821 |
| ADZ08277.1 | infB | Metbo_0024 | Metbo_0607 | PFAM: GTPase of unknown function C-terminal; GTP-binding protein, HSR1-related; TGS; KEGG: mth:MTH1515 translation-associated GTPase. | Translation initiation factor aIF-2; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. | 0.748 |
| ADZ08277.1 | leuS | Metbo_0024 | Metbo_0017 | PFAM: GTPase of unknown function C-terminal; GTP-binding protein, HSR1-related; TGS; KEGG: mth:MTH1515 translation-associated GTPase. | TIGRFAM: Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic; KEGG: mst:Msp_0171 leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.715 |
| ADZ08277.1 | metG | Metbo_0024 | Metbo_1344 | PFAM: GTPase of unknown function C-terminal; GTP-binding protein, HSR1-related; TGS; KEGG: mth:MTH1515 translation-associated GTPase. | Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.696 |
| ADZ08277.1 | pheT | Metbo_0024 | Metbo_0950 | PFAM: GTPase of unknown function C-terminal; GTP-binding protein, HSR1-related; TGS; KEGG: mth:MTH1515 translation-associated GTPase. | Phenylalanyl-tRNA synthetase beta chain; SMART: B3/B4 tRNA-binding domain; tRNA synthetase, B5; TIGRFAM: Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archae/euk cytosolic; KEGG: mmg:MTBMA_c11660 phenylalanyl-tRNA synthetase, beta chain; HAMAP: Phenylalanyl-tRNA synthetase beta chain 2, bacterial/archaeal; PFAM: tRNA synthetase, B5; B3/B4 tRNA-binding domain. | 0.715 |
| ADZ08277.1 | rpl13 | Metbo_0024 | Metbo_0810 | PFAM: GTPase of unknown function C-terminal; GTP-binding protein, HSR1-related; TGS; KEGG: mth:MTH1515 translation-associated GTPase. | Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.850 |
| ADZ08277.1 | rps2 | Metbo_0024 | Metbo_0816 | PFAM: GTPase of unknown function C-terminal; GTP-binding protein, HSR1-related; TGS; KEGG: mth:MTH1515 translation-associated GTPase. | KEGG: mth:MTH44 30S ribosomal protein S2; TIGRFAM: Ribosomal protein S2, eukaryotic/archaeal; PFAM: Ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 0.694 |
| ADZ08277.1 | rps7 | Metbo_0024 | Metbo_2391 | PFAM: GTPase of unknown function C-terminal; GTP-binding protein, HSR1-related; TGS; KEGG: mth:MTH1515 translation-associated GTPase. | Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family. | 0.753 |
| ADZ08277.1 | rps9 | Metbo_0024 | Metbo_0811 | PFAM: GTPase of unknown function C-terminal; GTP-binding protein, HSR1-related; TGS; KEGG: mth:MTH1515 translation-associated GTPase. | KEGG: mth:MTH39 ribosomal protein S16; TIGRFAM: Ribosomal protein S9, archaeal; PFAM: Ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family. | 0.850 |
| ADZ08354.1 | ADZ08277.1 | Metbo_0101 | Metbo_0024 | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. | PFAM: GTPase of unknown function C-terminal; GTP-binding protein, HSR1-related; TGS; KEGG: mth:MTH1515 translation-associated GTPase. | 0.746 |
| ADZ08354.1 | argS | Metbo_0101 | Metbo_0089 | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. | KEGG: mth:MTH1447 arginyl-tRNA synthetase; TIGRFAM: Arginyl-tRNA synthetase, class Ic; HAMAP: Arginyl-tRNA synthetase, class Ic; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.703 |
| ADZ08354.1 | infB | Metbo_0101 | Metbo_0607 | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. | Translation initiation factor aIF-2; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. | 0.891 |
| ADZ08354.1 | leuS | Metbo_0101 | Metbo_0017 | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. | TIGRFAM: Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic; KEGG: mst:Msp_0171 leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.753 |
| ADZ08354.1 | metG | Metbo_0101 | Metbo_1344 | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. | Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.532 |
| ADZ08354.1 | pheT | Metbo_0101 | Metbo_0950 | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. | Phenylalanyl-tRNA synthetase beta chain; SMART: B3/B4 tRNA-binding domain; tRNA synthetase, B5; TIGRFAM: Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archae/euk cytosolic; KEGG: mmg:MTBMA_c11660 phenylalanyl-tRNA synthetase, beta chain; HAMAP: Phenylalanyl-tRNA synthetase beta chain 2, bacterial/archaeal; PFAM: tRNA synthetase, B5; B3/B4 tRNA-binding domain. | 0.506 |
| ADZ08354.1 | rpl13 | Metbo_0101 | Metbo_0810 | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. | Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.811 |
| ADZ08354.1 | rps2 | Metbo_0101 | Metbo_0816 | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. | KEGG: mth:MTH44 30S ribosomal protein S2; TIGRFAM: Ribosomal protein S2, eukaryotic/archaeal; PFAM: Ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 0.587 |
| ADZ08354.1 | rps7 | Metbo_0101 | Metbo_2391 | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. | Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family. | 0.745 |
| ADZ08354.1 | rps9 | Metbo_0101 | Metbo_0811 | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. | KEGG: mth:MTH39 ribosomal protein S16; TIGRFAM: Ribosomal protein S9, archaeal; PFAM: Ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family. | 0.723 |