| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADZ08290.1 | ADZ08291.1 | Metbo_0037 | Metbo_0038 | Methanogenesis marker 13 metalloprotein; KEGG: msi:Msm_1160 nitrogenase molybdenum-iron protein, NifD; TIGRFAM: Putative methanogenesis marker 13 metalloprotein; PFAM: Nitrogenase/oxidoreductase, component 1. | PFAM: Nucleotidyl transferase; KEGG: mmg:MTBMA_c01060 nucleotidyl transferase. | 0.868 |
| ADZ08290.1 | ADZ08293.1 | Metbo_0037 | Metbo_0040 | Methanogenesis marker 13 metalloprotein; KEGG: msi:Msm_1160 nitrogenase molybdenum-iron protein, NifD; TIGRFAM: Putative methanogenesis marker 13 metalloprotein; PFAM: Nitrogenase/oxidoreductase, component 1. | PFAM: AIR synthase-related protein, C-terminal; AIR synthase-related protein; KEGG: mmg:MTBMA_c01080 HypE-related protein. | 0.794 |
| ADZ08290.1 | ADZ08604.1 | Metbo_0037 | Metbo_0352 | Methanogenesis marker 13 metalloprotein; KEGG: msi:Msm_1160 nitrogenase molybdenum-iron protein, NifD; TIGRFAM: Putative methanogenesis marker 13 metalloprotein; PFAM: Nitrogenase/oxidoreductase, component 1. | TIGRFAM: Methyl-coenzyme M reductase, gamma subunit; KEGG: mth:MTH1165 methyl coenzyme M reductase I, gamma subunit; PFAM: Methyl-coenzyme M reductase, gamma subunit. | 0.761 |
| ADZ08290.1 | ADZ08605.1 | Metbo_0037 | Metbo_0353 | Methanogenesis marker 13 metalloprotein; KEGG: msi:Msm_1160 nitrogenase molybdenum-iron protein, NifD; TIGRFAM: Putative methanogenesis marker 13 metalloprotein; PFAM: Nitrogenase/oxidoreductase, component 1. | Methyl-coenzyme M reductase, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis. | 0.762 |
| ADZ08290.1 | ADZ09424.1 | Metbo_0037 | Metbo_1180 | Methanogenesis marker 13 metalloprotein; KEGG: msi:Msm_1160 nitrogenase molybdenum-iron protein, NifD; TIGRFAM: Putative methanogenesis marker 13 metalloprotein; PFAM: Nitrogenase/oxidoreductase, component 1. | Nitrogenase; KEGG: mbn:Mboo_2008 nitrogenase iron protein; PFAM: Nitrogenase iron protein, subunit NifH/Protochlorophyllide reductase, subunit ChlL; Belongs to the NifH/BchL/ChlL family. | 0.836 |
| ADZ08290.1 | ADZ10556.1 | Metbo_0037 | Metbo_2343 | Methanogenesis marker 13 metalloprotein; KEGG: msi:Msm_1160 nitrogenase molybdenum-iron protein, NifD; TIGRFAM: Putative methanogenesis marker 13 metalloprotein; PFAM: Nitrogenase/oxidoreductase, component 1. | PFAM: Mur ligase, central; KEGG: mfv:Mfer_1205 mur ligase middle domain protein. | 0.984 |
| ADZ08290.1 | cbiA | Metbo_0037 | Metbo_0082 | Methanogenesis marker 13 metalloprotein; KEGG: msi:Msm_1160 nitrogenase molybdenum-iron protein, NifD; TIGRFAM: Putative methanogenesis marker 13 metalloprotein; PFAM: Nitrogenase/oxidoreductase, component 1. | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP- dependent amidation of the two carboxylate groups at positions a and c of Ni-sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source. | 0.765 |
| ADZ08290.1 | hisH | Metbo_0037 | Metbo_0039 | Methanogenesis marker 13 metalloprotein; KEGG: msi:Msm_1160 nitrogenase molybdenum-iron protein, NifD; TIGRFAM: Putative methanogenesis marker 13 metalloprotein; PFAM: Nitrogenase/oxidoreductase, component 1. | Imidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.777 |
| ADZ08290.1 | nifH | Metbo_0037 | Metbo_1819 | Methanogenesis marker 13 metalloprotein; KEGG: msi:Msm_1160 nitrogenase molybdenum-iron protein, NifD; TIGRFAM: Putative methanogenesis marker 13 metalloprotein; PFAM: Nitrogenase/oxidoreductase, component 1. | Nitrogenase iron protein; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein; Belongs to the NifH/BchL/ChlL family. | 0.833 |
| ADZ08290.1 | nifH-2 | Metbo_0037 | Metbo_2093 | Methanogenesis marker 13 metalloprotein; KEGG: msi:Msm_1160 nitrogenase molybdenum-iron protein, NifD; TIGRFAM: Putative methanogenesis marker 13 metalloprotein; PFAM: Nitrogenase/oxidoreductase, component 1. | Nitrogenase iron protein; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein; Belongs to the NifH/BchL/ChlL family. | 0.982 |
| ADZ08291.1 | ADZ08290.1 | Metbo_0038 | Metbo_0037 | PFAM: Nucleotidyl transferase; KEGG: mmg:MTBMA_c01060 nucleotidyl transferase. | Methanogenesis marker 13 metalloprotein; KEGG: msi:Msm_1160 nitrogenase molybdenum-iron protein, NifD; TIGRFAM: Putative methanogenesis marker 13 metalloprotein; PFAM: Nitrogenase/oxidoreductase, component 1. | 0.868 |
| ADZ08291.1 | ADZ08293.1 | Metbo_0038 | Metbo_0040 | PFAM: Nucleotidyl transferase; KEGG: mmg:MTBMA_c01060 nucleotidyl transferase. | PFAM: AIR synthase-related protein, C-terminal; AIR synthase-related protein; KEGG: mmg:MTBMA_c01080 HypE-related protein. | 0.889 |
| ADZ08291.1 | hisH | Metbo_0038 | Metbo_0039 | PFAM: Nucleotidyl transferase; KEGG: mmg:MTBMA_c01060 nucleotidyl transferase. | Imidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.929 |
| ADZ08293.1 | ADZ08290.1 | Metbo_0040 | Metbo_0037 | PFAM: AIR synthase-related protein, C-terminal; AIR synthase-related protein; KEGG: mmg:MTBMA_c01080 HypE-related protein. | Methanogenesis marker 13 metalloprotein; KEGG: msi:Msm_1160 nitrogenase molybdenum-iron protein, NifD; TIGRFAM: Putative methanogenesis marker 13 metalloprotein; PFAM: Nitrogenase/oxidoreductase, component 1. | 0.794 |
| ADZ08293.1 | ADZ08291.1 | Metbo_0040 | Metbo_0038 | PFAM: AIR synthase-related protein, C-terminal; AIR synthase-related protein; KEGG: mmg:MTBMA_c01080 HypE-related protein. | PFAM: Nucleotidyl transferase; KEGG: mmg:MTBMA_c01060 nucleotidyl transferase. | 0.889 |
| ADZ08293.1 | hisH | Metbo_0040 | Metbo_0039 | PFAM: AIR synthase-related protein, C-terminal; AIR synthase-related protein; KEGG: mmg:MTBMA_c01080 HypE-related protein. | Imidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.841 |
| ADZ08604.1 | ADZ08290.1 | Metbo_0352 | Metbo_0037 | TIGRFAM: Methyl-coenzyme M reductase, gamma subunit; KEGG: mth:MTH1165 methyl coenzyme M reductase I, gamma subunit; PFAM: Methyl-coenzyme M reductase, gamma subunit. | Methanogenesis marker 13 metalloprotein; KEGG: msi:Msm_1160 nitrogenase molybdenum-iron protein, NifD; TIGRFAM: Putative methanogenesis marker 13 metalloprotein; PFAM: Nitrogenase/oxidoreductase, component 1. | 0.761 |
| ADZ08604.1 | ADZ08605.1 | Metbo_0352 | Metbo_0353 | TIGRFAM: Methyl-coenzyme M reductase, gamma subunit; KEGG: mth:MTH1165 methyl coenzyme M reductase I, gamma subunit; PFAM: Methyl-coenzyme M reductase, gamma subunit. | Methyl-coenzyme M reductase, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis. | 0.999 |
| ADZ08604.1 | ADZ10556.1 | Metbo_0352 | Metbo_2343 | TIGRFAM: Methyl-coenzyme M reductase, gamma subunit; KEGG: mth:MTH1165 methyl coenzyme M reductase I, gamma subunit; PFAM: Methyl-coenzyme M reductase, gamma subunit. | PFAM: Mur ligase, central; KEGG: mfv:Mfer_1205 mur ligase middle domain protein. | 0.632 |
| ADZ08605.1 | ADZ08290.1 | Metbo_0353 | Metbo_0037 | Methyl-coenzyme M reductase, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis. | Methanogenesis marker 13 metalloprotein; KEGG: msi:Msm_1160 nitrogenase molybdenum-iron protein, NifD; TIGRFAM: Putative methanogenesis marker 13 metalloprotein; PFAM: Nitrogenase/oxidoreductase, component 1. | 0.762 |
