STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADZ08293.1PFAM: AIR synthase-related protein, C-terminal; AIR synthase-related protein; KEGG: mmg:MTBMA_c01080 HypE-related protein. (454 aa)    
Predicted Functional Partners:
ADZ08291.1
PFAM: Nucleotidyl transferase; KEGG: mmg:MTBMA_c01060 nucleotidyl transferase.
 
     0.859
hisH
Imidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
       0.821
ADZ08348.1
UPF0285 protein; KEGG: mmg:MTBMA_c00280 putative carbohydrate kinase of the FGGY family; TIGRFAM: Uncharacterised protein family UPF0285, methanogenesis; HAMAP: Uncharacterised protein family UPF0285, methanogenesis; Belongs to the UPF0285 family.
  
     0.708
ADZ08290.1
Methanogenesis marker 13 metalloprotein; KEGG: msi:Msm_1160 nitrogenase molybdenum-iron protein, NifD; TIGRFAM: Putative methanogenesis marker 13 metalloprotein; PFAM: Nitrogenase/oxidoreductase, component 1.
 
     0.705
rpl13
Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
       0.703
rps9
KEGG: mth:MTH39 ribosomal protein S16; TIGRFAM: Ribosomal protein S9, archaeal; PFAM: Ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.
       0.703
ADZ08600.1
Methanogenesis marker protein 10; KEGG: mmg:MTBMA_c15530 Fe-S oxidoreductase; TIGRFAM: Putative methanogenesis marker protein 10; PFAM: Domain of unknown function DUF512; Radical SAM.
  
     0.695
mtrE
Tetrahydromethanopterin S-methyltransferase subunit E; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.
  
     0.691
mtrD
Tetrahydromethanopterin S-methyltransferase subunit D; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.
  
     0.688
mtrG
Tetrahydromethanopterin S-methyltransferase, subunit G; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.
  
     0.688
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
Server load: medium (52%) [HD]