Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADZ08294.1KEGG: mru:mru_0196 hypothetical protein. (143 aa)    
Predicted Functional Partners:
ADZ08291.1
PFAM: Nucleotidyl transferase; KEGG: mmg:MTBMA_c01060 nucleotidyl transferase.
       0.783
ADZ08293.1
PFAM: AIR synthase-related protein, C-terminal; AIR synthase-related protein; KEGG: mmg:MTBMA_c01080 HypE-related protein.
       0.665
hisH
Imidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
       0.511
ADZ08295.1
Phosphoesterase PA-phosphatase related protein; PFAM: Phosphatidic acid phosphatase type 2/haloperoxidase; KEGG: mpl:Mpal_0753 hypothetical protein.
       0.463
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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