| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADZ08298.1 | ADZ08299.1 | Metbo_0045 | Metbo_0046 | Protein of unknown function DUF120; PFAM: Riboflavin kinase, CTP-dependent, archaeal; KEGG: mru:mru_2174 riboflavin kinase RibK. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 0.804 |
| ADZ08298.1 | ADZ08637.1 | Metbo_0045 | Metbo_0385 | Protein of unknown function DUF120; PFAM: Riboflavin kinase, CTP-dependent, archaeal; KEGG: mru:mru_2174 riboflavin kinase RibK. | tRNA ribose 2'-O-methyltransferase aTrm56; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | 0.640 |
| ADZ08298.1 | ADZ08851.1 | Metbo_0045 | Metbo_0600 | Protein of unknown function DUF120; PFAM: Riboflavin kinase, CTP-dependent, archaeal; KEGG: mru:mru_2174 riboflavin kinase RibK. | UPF0218 protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). | 0.686 |
| ADZ08298.1 | ADZ08932.1 | Metbo_0045 | Metbo_0681 | Protein of unknown function DUF120; PFAM: Riboflavin kinase, CTP-dependent, archaeal; KEGG: mru:mru_2174 riboflavin kinase RibK. | SMART: Nucleotide binding protein, PINc; KEGG: mru:mru_1781 hypothetical protein. | 0.592 |
| ADZ08298.1 | ADZ09239.1 | Metbo_0045 | Metbo_0992 | Protein of unknown function DUF120; PFAM: Riboflavin kinase, CTP-dependent, archaeal; KEGG: mru:mru_2174 riboflavin kinase RibK. | PFAM: Cytidylyltransferase; TIGRFAM: Nicotinamide-nucleotide adenylyltransferase, archaeal type; Cytidyltransferase-related; HAMAP: Nicotinamide-nucleotide adenylyltransferase, archaeal type; KEGG: mmg:MTBMA_c06000 nicotinamide-nucleotide adenylyltransferase. | 0.613 |
| ADZ08298.1 | ADZ10341.1 | Metbo_0045 | Metbo_2122 | Protein of unknown function DUF120; PFAM: Riboflavin kinase, CTP-dependent, archaeal; KEGG: mru:mru_2174 riboflavin kinase RibK. | GHMP kinase; KEGG: mst:Msp_1187 kinase; manually curated; PFAM: GHMP kinase. | 0.597 |
| ADZ08298.1 | ADZ10408.1 | Metbo_0045 | Metbo_2194 | Protein of unknown function DUF120; PFAM: Riboflavin kinase, CTP-dependent, archaeal; KEGG: mru:mru_2174 riboflavin kinase RibK. | TIGRFAM: Riboflavin synthase, archaeal; KEGG: mst:Msp_1239 riboflavin synthase; PFAM: 6,7-dimethyl-8-ribityllumazine synthase. | 0.912 |
| ADZ08298.1 | ribL | Metbo_0045 | Metbo_1957 | Protein of unknown function DUF120; PFAM: Riboflavin kinase, CTP-dependent, archaeal; KEGG: mru:mru_2174 riboflavin kinase RibK. | Cytidyltransferase-related domain protein; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme. | 0.943 |
| ADZ08298.1 | sepS | Metbo_0045 | Metbo_0044 | Protein of unknown function DUF120; PFAM: Riboflavin kinase, CTP-dependent, archaeal; KEGG: mru:mru_2174 riboflavin kinase RibK. | O-phosphoseryl-tRNA(Cys) synthetase; Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys). | 0.627 |
| ADZ08298.1 | tiaS | Metbo_0045 | Metbo_0426 | Protein of unknown function DUF120; PFAM: Riboflavin kinase, CTP-dependent, archaeal; KEGG: mru:mru_2174 riboflavin kinase RibK. | Domain of unknown function DUF1743; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA. | 0.692 |
| ADZ08299.1 | ADZ08298.1 | Metbo_0046 | Metbo_0045 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | Protein of unknown function DUF120; PFAM: Riboflavin kinase, CTP-dependent, archaeal; KEGG: mru:mru_2174 riboflavin kinase RibK. | 0.804 |
| ADZ08299.1 | ADZ10408.1 | Metbo_0046 | Metbo_2194 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | TIGRFAM: Riboflavin synthase, archaeal; KEGG: mst:Msp_1239 riboflavin synthase; PFAM: 6,7-dimethyl-8-ribityllumazine synthase. | 0.595 |
| ADZ08299.1 | sepS | Metbo_0046 | Metbo_0044 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | O-phosphoseryl-tRNA(Cys) synthetase; Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys). | 0.468 |
| ADZ08637.1 | ADZ08298.1 | Metbo_0385 | Metbo_0045 | tRNA ribose 2'-O-methyltransferase aTrm56; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | Protein of unknown function DUF120; PFAM: Riboflavin kinase, CTP-dependent, archaeal; KEGG: mru:mru_2174 riboflavin kinase RibK. | 0.640 |
| ADZ08637.1 | ADZ08851.1 | Metbo_0385 | Metbo_0600 | tRNA ribose 2'-O-methyltransferase aTrm56; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | UPF0218 protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). | 0.549 |
| ADZ08637.1 | ADZ08932.1 | Metbo_0385 | Metbo_0681 | tRNA ribose 2'-O-methyltransferase aTrm56; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | SMART: Nucleotide binding protein, PINc; KEGG: mru:mru_1781 hypothetical protein. | 0.588 |
| ADZ08637.1 | ADZ09239.1 | Metbo_0385 | Metbo_0992 | tRNA ribose 2'-O-methyltransferase aTrm56; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | PFAM: Cytidylyltransferase; TIGRFAM: Nicotinamide-nucleotide adenylyltransferase, archaeal type; Cytidyltransferase-related; HAMAP: Nicotinamide-nucleotide adenylyltransferase, archaeal type; KEGG: mmg:MTBMA_c06000 nicotinamide-nucleotide adenylyltransferase. | 0.660 |
| ADZ08637.1 | ADZ10341.1 | Metbo_0385 | Metbo_2122 | tRNA ribose 2'-O-methyltransferase aTrm56; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | GHMP kinase; KEGG: mst:Msp_1187 kinase; manually curated; PFAM: GHMP kinase. | 0.405 |
| ADZ08637.1 | tiaS | Metbo_0385 | Metbo_0426 | tRNA ribose 2'-O-methyltransferase aTrm56; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | Domain of unknown function DUF1743; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA. | 0.674 |
| ADZ08851.1 | ADZ08298.1 | Metbo_0600 | Metbo_0045 | UPF0218 protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). | Protein of unknown function DUF120; PFAM: Riboflavin kinase, CTP-dependent, archaeal; KEGG: mru:mru_2174 riboflavin kinase RibK. | 0.686 |