Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADZ08322.1PFAM: Protein of unknown function DUF1786, putative pyruvate format-lyase activating enzyme; KEGG: mmg:MTBMA_c00600 hypothetical protein. (336 aa)    
Predicted Functional Partners:
ADZ08321.1
PHP domain protein; KEGG: mmg:MTBMA_c00610 phosphoesterase; PFAM: PHP, C-terminal; SMART: Polymerase/histidinol phosphatase, N-terminal.
       0.789
ADZ08320.1
PFAM: Protein of unknown function DUF63; KEGG: mth:MTH1480 hypothetical protein.
 
     0.699
trpB
Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
       0.528
ADZ10439.1
Protein of unknown function UPF0146; PFAM: Uncharacterised protein family UPF0146; KEGG: mmg:MTBMA_c13820 hypothetical protein; Belongs to the UPF0146 family.
  
     0.415
ADZ08319.1
SMART: 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain; TIGRFAM: Isopropylmalate/citramalate/homocitrate synthase; KEGG: mth:MTH1481 2-isopropylmalate synthase; PFAM: Pyruvate carboxyltransferase; 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain; Belongs to the alpha-IPM synthase/homocitrate synthase family.
       0.411
ADZ09418.1
PFAM: Amino acid-binding ACT; KEGG: msi:Msm_0155 allosteric regulator of homoserine dehydrogenase.
  
     0.403
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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