Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADZ08325.1PFAM: Cobalamin (vitamin B12) biosynthesis CbiM; KEGG: mru:mru_0539 cobalamin biosynthesis protein CbiM1. (223 aa)    
Predicted Functional Partners:
ADZ08326.1
KEGG: mth:MTH1706 cobalt transport protein CbiN.
 
 
 0.998
ADZ08327.1
Cobalt ABC transporter, inner membrane subunit CbiQ; KEGG: mru:mru_0541 cobalt ABC transporter permease protein CbiQ1; TIGRFAM: Cobalt ABC transporter CbiQ, permease subunit; PFAM: Cobalt transport protein.
 
 
 0.989
ADZ09005.1
KEGG: mfv:Mfer_0953 cobalt abc transporter, inner membrane subunit CbiQ; TIGRFAM: Cobalt ABC transporter CbiQ, permease subunit; PFAM: Cobalt transport protein.
 
 
 0.987
cbiN
Cobalt transport protein; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import; Belongs to the CbiN family.
 
 
 0.977
ecfA
Cobalt ABC transporter, ATPase subunit; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
 
 
 0.969
cbiM
Cobalamin biosynthesis protein CbiM; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.
  
  
0.917
ADZ10271.1
PFAM: Formylmethanofuran dehydrogenase, subunit E domain; KEGG: mac:MA4602 formylmethanofuran dehydrogenase, subunit E.
  
    0.722
ADZ10700.1
PFAM: Formylmethanofuran dehydrogenase, subunit E domain; KEGG: msi:Msm_1396 tungsten formylmethanofuran dehydrogenase, subunit E, FwdE.
  
    0.722
ADZ10633.1
1-(5-phosphoribosyl)-5-amino-4-imidazole- carboxylate (AIR) carboxylase; PFAM: Phosphoribosylaminoimidazole carboxylase, core; Protein of unknown function DUF2089; KEGG: msi:Msm_1105 NCAIR mutase related protein, PurE.
 
    0.607
ADZ10448.1
TIGRFAM: Conserved hypothetical protein CHP00268; KEGG: mmg:MTBMA_c13730 ATP-utilizing enzyme.
 
    0.588
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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