STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADZ08328.1PFAM: NADPH-dependent FMN reductase; KEGG: afu:AF1519 iron-sulfur flavoprotein (isf-2). (197 aa)    
Predicted Functional Partners:
ADZ09692.1
PFAM: NADPH-dependent FMN reductase; KEGG: mac:MA3658 iron-sulfur flavoprotein.
  
     0.670
ADZ08331.1
KEGG: mpd:MCP_0414 hypothetical protein.
 
   
 0.564
hisB
HAMAP: Imidazoleglycerol-phosphate dehydratase; KEGG: mru:mru_2139 bifunctional imidazoleglycerol-phosphate dehydratase HisB; PFAM: Imidazoleglycerol-phosphate dehydratase.
  
    0.511
ADZ09051.1
PFAM: Protein of unknown function DUF106, transmembrane; KEGG: mmg:MTBMA_c05170 hypothetical protein.
   
    0.499
ADZ08329.1
PFAM: 4Fe-4S binding domain; KEGG: mmg:MTBMA_c00530 ferredoxin.
     
 0.484
ADZ10672.1
Manually curated; TIGRFAM: Archaeoflavoprotein AfpA; KEGG: mtp:Mthe_0245 flavoprotein; PFAM: Flavoprotein.
 
    0.468
ADZ10535.1
Archaeoflavoprotein AfpA; KEGG: mtp:Mthe_0245 flavoprotein; TIGRFAM: Archaeoflavoprotein AfpA; PFAM: Flavoprotein.
 
    0.463
aroA-2
Phospho-2-dehydro-3-deoxyheptonate aldolase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.
 
    0.415
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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