Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADZ08332.1KEGG: sfu:Sfum_0396 HAD superfamily hydrolase. (406 aa)    
Predicted Functional Partners:
mtd
F420-dependent methylenetetrahydromethanopterin dehydrogenase; Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT.
       0.551
ADZ09016.1
PFAM: Methyltransferase type 11; KEGG: msi:Msm_0764 ribosomal L11 RNA methyltransferase (SAM-dependent).
   
    0.473
ADZ09238.1
PFAM: Molybdopterin biosynthesis MoaE; KEGG: mru:mru_1268 molybdenum cofactor biosynthesis protein MoaE.
  
    0.419
ADZ08988.1
PFAM: GTP-binding protein, HSR1-related; KEGG: mmg:MTBMA_c04750 GTP-binding protein.
       0.402
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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