Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADZ08338.1PFAM: Cobyrinic acid a,c-diamide synthase; KEGG: mmg:MTBMA_c00420 ATPase. (261 aa)    
Predicted Functional Partners:
ADZ08337.1
KEGG: mst:Msp_1570 hypothetical protein.
     
 0.817
ADZ08567.1
Putative signal transduction protein with CBS domains; KEGG: mmg:MTBMA_c16670 CBS domain containing protein; PFAM: Cystathionine beta-synthase, core; ParB-like nuclease; SMART: ParB-like nuclease; Cystathionine beta-synthase, core.
  
 
 0.786
ADZ09104.1
PFAM: Glycosyl transferase, family 2; KEGG: has:Halsa_0644 undecaprenyl-phosphate galactose phosphotransferase.
  
 
 0.740
ADZ09890.1
PFAM: Glycosyl transferase, family 2; KEGG: mem:Memar_1704 glycosyl transferase family protein.
  
 
 0.740
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
  
 0.577
thrS
TIGRFAM: Threonyl-tRNA synthetase, class IIa; KEGG: mth:MTH1455 threonyl-tRNA synthetase; PFAM: Threonyl-tRNA synthetase, editing domain, archaea; Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved domain; Anticodon-binding; Belongs to the class-II aminoacyl-tRNA synthetase family.
  
  
 0.505
srp54
Signal recognition 54 kDa protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
  
  
 0.473
hisS
ATP phosphoribosyltransferase regulatory subunit; PFAM: Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved domain; Anticodon-binding; TIGRFAM: Histidyl-tRNA synthetase, class IIa, subgroup; HAMAP: ATP phosphoribosyltransferase regulatory subunit; Histidyl-tRNA synthetase, class IIa, subgroup; KEGG: mth:MTH244 histidyl-tRNA synthetase.
  
    0.448
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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