| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADZ08360.1 | ADZ08378.1 | Metbo_0107 | Metbo_0125 | Helicase domain protein; KEGG: mth:MTH1415 Hef nuclease; PFAM: Helicase, C-terminal; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; ERCC4 domain; Helix-hairpin-helix motif; SMART: DEAD-like helicase, N-terminal; Helicase, C-terminal; ERCC4 domain; Helix-hairpin-helix DNA-binding motif, class 1. | DNA-(apurinic or apyrimidinic site) lyase; PFAM: 8-oxoguanine DNA glycosylase, N-terminal; HhH-GPD domain; KEGG: msi:Msm_1365 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase; SMART: HhH-GPD domain. | 0.700 |
| ADZ08360.1 | ADZ09784.1 | Metbo_0107 | Metbo_1557 | Helicase domain protein; KEGG: mth:MTH1415 Hef nuclease; PFAM: Helicase, C-terminal; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; ERCC4 domain; Helix-hairpin-helix motif; SMART: DEAD-like helicase, N-terminal; Helicase, C-terminal; ERCC4 domain; Helix-hairpin-helix DNA-binding motif, class 1. | KEGG: mbu:Mbur_2162 helicase-like protein; PFAM: Helicase, C-terminal; Restriction endonuclease, type I, R subunit/Type III, Res subunit; SMART: Helicase, C-terminal; DEAD-like helicase, N-terminal. | 0.750 |
| ADZ08360.1 | ADZ10658.1 | Metbo_0107 | Metbo_2445 | Helicase domain protein; KEGG: mth:MTH1415 Hef nuclease; PFAM: Helicase, C-terminal; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; ERCC4 domain; Helix-hairpin-helix motif; SMART: DEAD-like helicase, N-terminal; Helicase, C-terminal; ERCC4 domain; Helix-hairpin-helix DNA-binding motif, class 1. | KEGG: msi:Msm_0963 endonuclease IV; PFAM: Xylose isomerase, TIM barrel domain; SMART: Endodeoxyribonuclease IV. | 0.620 |
| ADZ08360.1 | radA | Metbo_0107 | Metbo_0166 | Helicase domain protein; KEGG: mth:MTH1415 Hef nuclease; PFAM: Helicase, C-terminal; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; ERCC4 domain; Helix-hairpin-helix motif; SMART: DEAD-like helicase, N-terminal; Helicase, C-terminal; ERCC4 domain; Helix-hairpin-helix DNA-binding motif, class 1. | DNA repair and recombination protein radA; Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules. | 0.810 |
| ADZ08360.1 | radB | Metbo_0107 | Metbo_0588 | Helicase domain protein; KEGG: mth:MTH1415 Hef nuclease; PFAM: Helicase, C-terminal; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; ERCC4 domain; Helix-hairpin-helix motif; SMART: DEAD-like helicase, N-terminal; Helicase, C-terminal; ERCC4 domain; Helix-hairpin-helix DNA-binding motif, class 1. | DNA repair and recombination protein radB; Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange. | 0.815 |
| ADZ08360.1 | uvrC | Metbo_0107 | Metbo_1143 | Helicase domain protein; KEGG: mth:MTH1415 Hef nuclease; PFAM: Helicase, C-terminal; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; ERCC4 domain; Helix-hairpin-helix motif; SMART: DEAD-like helicase, N-terminal; Helicase, C-terminal; ERCC4 domain; Helix-hairpin-helix DNA-binding motif, class 1. | UvrABC system protein C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.858 |
| ADZ08377.1 | ADZ08378.1 | Metbo_0124 | Metbo_0125 | KEGG: mfv:Mfer_0071 hypothetical protein. | DNA-(apurinic or apyrimidinic site) lyase; PFAM: 8-oxoguanine DNA glycosylase, N-terminal; HhH-GPD domain; KEGG: msi:Msm_1365 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase; SMART: HhH-GPD domain. | 0.667 |
| ADZ08378.1 | ADZ08360.1 | Metbo_0125 | Metbo_0107 | DNA-(apurinic or apyrimidinic site) lyase; PFAM: 8-oxoguanine DNA glycosylase, N-terminal; HhH-GPD domain; KEGG: msi:Msm_1365 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase; SMART: HhH-GPD domain. | Helicase domain protein; KEGG: mth:MTH1415 Hef nuclease; PFAM: Helicase, C-terminal; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; ERCC4 domain; Helix-hairpin-helix motif; SMART: DEAD-like helicase, N-terminal; Helicase, C-terminal; ERCC4 domain; Helix-hairpin-helix DNA-binding motif, class 1. | 0.700 |
| ADZ08378.1 | ADZ08377.1 | Metbo_0125 | Metbo_0124 | DNA-(apurinic or apyrimidinic site) lyase; PFAM: 8-oxoguanine DNA glycosylase, N-terminal; HhH-GPD domain; KEGG: msi:Msm_1365 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase; SMART: HhH-GPD domain. | KEGG: mfv:Mfer_0071 hypothetical protein. | 0.667 |
| ADZ08378.1 | ADZ09784.1 | Metbo_0125 | Metbo_1557 | DNA-(apurinic or apyrimidinic site) lyase; PFAM: 8-oxoguanine DNA glycosylase, N-terminal; HhH-GPD domain; KEGG: msi:Msm_1365 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase; SMART: HhH-GPD domain. | KEGG: mbu:Mbur_2162 helicase-like protein; PFAM: Helicase, C-terminal; Restriction endonuclease, type I, R subunit/Type III, Res subunit; SMART: Helicase, C-terminal; DEAD-like helicase, N-terminal. | 0.670 |
| ADZ08378.1 | ADZ10658.1 | Metbo_0125 | Metbo_2445 | DNA-(apurinic or apyrimidinic site) lyase; PFAM: 8-oxoguanine DNA glycosylase, N-terminal; HhH-GPD domain; KEGG: msi:Msm_1365 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase; SMART: HhH-GPD domain. | KEGG: msi:Msm_0963 endonuclease IV; PFAM: Xylose isomerase, TIM barrel domain; SMART: Endodeoxyribonuclease IV. | 0.746 |
| ADZ08378.1 | ADZ10662.1 | Metbo_0125 | Metbo_2449 | DNA-(apurinic or apyrimidinic site) lyase; PFAM: 8-oxoguanine DNA glycosylase, N-terminal; HhH-GPD domain; KEGG: msi:Msm_1365 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase; SMART: HhH-GPD domain. | TIGRFAM: Exodeoxyribonuclease III xth; AP endonuclease, family 1; KEGG: mmg:MTBMA_c06610 DNA lyase; PFAM: Endonuclease/exonuclease/phosphatase. | 0.862 |
| ADZ08378.1 | hisF | Metbo_0125 | Metbo_0131 | DNA-(apurinic or apyrimidinic site) lyase; PFAM: 8-oxoguanine DNA glycosylase, N-terminal; HhH-GPD domain; KEGG: msi:Msm_1365 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase; SMART: HhH-GPD domain. | Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.661 |
| ADZ08378.1 | nth | Metbo_0125 | Metbo_0940 | DNA-(apurinic or apyrimidinic site) lyase; PFAM: 8-oxoguanine DNA glycosylase, N-terminal; HhH-GPD domain; KEGG: msi:Msm_1365 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase; SMART: HhH-GPD domain. | DNA-(apurinic or apyrimidinic site) lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.768 |
| ADZ08378.1 | radA | Metbo_0125 | Metbo_0166 | DNA-(apurinic or apyrimidinic site) lyase; PFAM: 8-oxoguanine DNA glycosylase, N-terminal; HhH-GPD domain; KEGG: msi:Msm_1365 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase; SMART: HhH-GPD domain. | DNA repair and recombination protein radA; Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules. | 0.550 |
| ADZ08378.1 | radB | Metbo_0125 | Metbo_0588 | DNA-(apurinic or apyrimidinic site) lyase; PFAM: 8-oxoguanine DNA glycosylase, N-terminal; HhH-GPD domain; KEGG: msi:Msm_1365 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase; SMART: HhH-GPD domain. | DNA repair and recombination protein radB; Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange. | 0.541 |
| ADZ08378.1 | uvrC | Metbo_0125 | Metbo_1143 | DNA-(apurinic or apyrimidinic site) lyase; PFAM: 8-oxoguanine DNA glycosylase, N-terminal; HhH-GPD domain; KEGG: msi:Msm_1365 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase; SMART: HhH-GPD domain. | UvrABC system protein C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.592 |
| ADZ09784.1 | ADZ08360.1 | Metbo_1557 | Metbo_0107 | KEGG: mbu:Mbur_2162 helicase-like protein; PFAM: Helicase, C-terminal; Restriction endonuclease, type I, R subunit/Type III, Res subunit; SMART: Helicase, C-terminal; DEAD-like helicase, N-terminal. | Helicase domain protein; KEGG: mth:MTH1415 Hef nuclease; PFAM: Helicase, C-terminal; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; ERCC4 domain; Helix-hairpin-helix motif; SMART: DEAD-like helicase, N-terminal; Helicase, C-terminal; ERCC4 domain; Helix-hairpin-helix DNA-binding motif, class 1. | 0.750 |
| ADZ09784.1 | ADZ08378.1 | Metbo_1557 | Metbo_0125 | KEGG: mbu:Mbur_2162 helicase-like protein; PFAM: Helicase, C-terminal; Restriction endonuclease, type I, R subunit/Type III, Res subunit; SMART: Helicase, C-terminal; DEAD-like helicase, N-terminal. | DNA-(apurinic or apyrimidinic site) lyase; PFAM: 8-oxoguanine DNA glycosylase, N-terminal; HhH-GPD domain; KEGG: msi:Msm_1365 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase; SMART: HhH-GPD domain. | 0.670 |
| ADZ09784.1 | ADZ10658.1 | Metbo_1557 | Metbo_2445 | KEGG: mbu:Mbur_2162 helicase-like protein; PFAM: Helicase, C-terminal; Restriction endonuclease, type I, R subunit/Type III, Res subunit; SMART: Helicase, C-terminal; DEAD-like helicase, N-terminal. | KEGG: msi:Msm_0963 endonuclease IV; PFAM: Xylose isomerase, TIM barrel domain; SMART: Endodeoxyribonuclease IV. | 0.486 |
