STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADZ08378.1DNA-(apurinic or apyrimidinic site) lyase; PFAM: 8-oxoguanine DNA glycosylase, N-terminal; HhH-GPD domain; KEGG: msi:Msm_1365 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase; SMART: HhH-GPD domain. (328 aa)    
Predicted Functional Partners:
ADZ10662.1
TIGRFAM: Exodeoxyribonuclease III xth; AP endonuclease, family 1; KEGG: mmg:MTBMA_c06610 DNA lyase; PFAM: Endonuclease/exonuclease/phosphatase.
  
 0.813
ADZ10658.1
KEGG: msi:Msm_0963 endonuclease IV; PFAM: Xylose isomerase, TIM barrel domain; SMART: Endodeoxyribonuclease IV.
   
 
 0.722
ADZ09784.1
KEGG: mbu:Mbur_2162 helicase-like protein; PFAM: Helicase, C-terminal; Restriction endonuclease, type I, R subunit/Type III, Res subunit; SMART: Helicase, C-terminal; DEAD-like helicase, N-terminal.
  
 
 0.701
ADZ08360.1
Helicase domain protein; KEGG: mth:MTH1415 Hef nuclease; PFAM: Helicase, C-terminal; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; ERCC4 domain; Helix-hairpin-helix motif; SMART: DEAD-like helicase, N-terminal; Helicase, C-terminal; ERCC4 domain; Helix-hairpin-helix DNA-binding motif, class 1.
    
 
 0.682
ADZ08377.1
KEGG: mfv:Mfer_0071 hypothetical protein.
       0.639
hisF
Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
     
 0.574
ADZ08379.1
Agmatinase; TIGRFAM: Putative agmatinase; KEGG: ara:Arad_7959 agmatinase; PFAM: Ureohydrolase; Belongs to the arginase family.
       0.535
ADZ08381.1
PFAM: Methylpurine-DNA glycosylase (MPG); TIGRFAM: Methylpurine-DNA glycosylase (MPG); HAMAP: Methylpurine-DNA glycosylase (MPG); KEGG: ccb:Clocel_1348 DNA-3-methyladenine glycosylase; Belongs to the DNA glycosylase MPG family.
 
   
 0.509
ADZ08376.1
GAF domain protein; KEGG: mmg:MTBMA_c17210 signal transduction protein; PFAM: GAF; SMART: GAF.
       0.507
ADZ08382.1
KEGG: glo:Glov_0058 DNA-3-methyladenine glycosylase I; PFAM: Methyladenine glycosylase.
     
 0.458
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.