Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADZ08383.1PFAM: Isochorismatase-like; KEGG: mpl:Mpal_1179 isochorismatase hydrolase. (200 aa)    
Predicted Functional Partners:
ADZ08897.1
Nicotinate-nucleotide pyrophosphorylase; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family.
  
 
 0.637
nadE
NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
  
  
 0.597
ADZ08381.1
PFAM: Methylpurine-DNA glycosylase (MPG); TIGRFAM: Methylpurine-DNA glycosylase (MPG); HAMAP: Methylpurine-DNA glycosylase (MPG); KEGG: ccb:Clocel_1348 DNA-3-methyladenine glycosylase; Belongs to the DNA glycosylase MPG family.
  
  
 0.575
ADZ08382.1
KEGG: glo:Glov_0058 DNA-3-methyladenine glycosylase I; PFAM: Methyladenine glycosylase.
       0.533
rps12
Ribosomal protein S23 (S12); With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family.
  
  
 0.523
ADZ10102.1
PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: mru:mru_0603 N-carbamoyl-D-amino acid amidohydrolase AguB.
  
 
 0.511
ADZ09848.1
Chloride peroxidase; KEGG: mpl:Mpal_2171 alpha/beta hydrolase fold protein; PFAM: Alpha/beta hydrolase fold-1.
 
 
 0.484
nnrE
YjeF-related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epi [...]
  
  
 0.471
ADZ09639.1
KEGG: mba:Mbar_A1645 phenylacetic acid degradation protein; TIGRFAM: Phenylacetic acid degradation-related protein; PFAM: Thioesterase superfamily.
     
 0.471
ADZ08380.1
KEGG: mst:Msp_0033 hypothetical protein.
  
  
 0.452
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.