STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADZ08398.1Peptidase M50; KEGG: mmg:MTBMA_c17550 protease; PFAM: Peptidase M50; PDZ/DHR/GLGF; SMART: PDZ/DHR/GLGF. (415 aa)    
Predicted Functional Partners:
ADZ08399.1
TIGRFAM: Molybdenum cofactor synthesis; PFAM: MoeA, N-terminal and linker domain; Molybdopterin binding; MoeA, C-terminal, domain IV; KEGG: mmg:MTBMA_c17560 molybdenum cofactor biosynthesis protein; SMART: Molybdopterin binding.
       0.791
uppS
Undecaprenyl pyrophosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.
 
  
 0.716
ADZ08363.1
Cell division control protein 6-like protein; Involved in regulation of DNA replication.
  
     0.684
endA
tRNA-splicing endonuclease; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
  
     0.645
ADZ08315.1
KEGG: mmg:MTBMA_c00680 hypothetical protein; PFAM: Pyrrolo-quinoline quinone repeat; SMART: Pyrrolo-quinoline quinone beta-propeller repeat.
 
  
 0.637
ADZ08357.1
PFAM: Phosphoesterase, RecJ-like; Phosphoesterase, DHHA1; KEGG: msi:Msm_1193 single-stranded DNA-specific exonuclease.
 
    0.608
eif5a
Translation initiation factor 5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.
 
     0.600
ADZ10339.1
PFAM: Phosphoesterase, DHHA1; Phosphoesterase, RecJ-like; KEGG: mst:Msp_1189 hypothetical protein.
 
    0.590
gatA
Glutamyl-tRNA(Gln) amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln).
  
  
 0.563
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
 
  
 0.553
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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