Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADZ08398.1Peptidase M50; KEGG: mmg:MTBMA_c17550 protease; PFAM: Peptidase M50; PDZ/DHR/GLGF; SMART: PDZ/DHR/GLGF. (415 aa)    
Predicted Functional Partners:
ADZ08399.1
TIGRFAM: Molybdenum cofactor synthesis; PFAM: MoeA, N-terminal and linker domain; Molybdopterin binding; MoeA, C-terminal, domain IV; KEGG: mmg:MTBMA_c17560 molybdenum cofactor biosynthesis protein; SMART: Molybdopterin binding.
     
 0.851
uppS
Undecaprenyl pyrophosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.
 
  
 0.691
ADZ08363.1
Cell division control protein 6-like protein; Involved in regulation of DNA replication.
  
     0.684
eif5a
Translation initiation factor 5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.
 
   
 0.653
endA
tRNA-splicing endonuclease; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
  
     0.645
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
  
  
 0.612
ADZ08357.1
PFAM: Phosphoesterase, RecJ-like; Phosphoesterase, DHHA1; KEGG: msi:Msm_1193 single-stranded DNA-specific exonuclease.
 
    0.605
ADZ10339.1
PFAM: Phosphoesterase, DHHA1; Phosphoesterase, RecJ-like; KEGG: mst:Msp_1189 hypothetical protein.
 
    0.586
ADZ08315.1
KEGG: mmg:MTBMA_c00680 hypothetical protein; PFAM: Pyrrolo-quinoline quinone repeat; SMART: Pyrrolo-quinoline quinone beta-propeller repeat.
 
  
 0.575
dnaG
UPF0095 protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.
 
    0.563
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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