Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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[Homology]
Score
ADZ08412.1KEGG: mmg:MTBMA_c17650 hypothetical protein; PFAM: PBS lyase HEAT-like repeat; SMART: PBS lyase HEAT-like repeat. (128 aa)    
Predicted Functional Partners:
eif5a
Translation initiation factor 5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.
  
 0.816
trpE
Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...]
 
   0.495
ADZ08413.1
Archaeoflavoprotein, MJ0208 family; KEGG: mmg:MTBMA_c17660 conserved hypothetical protein containing a ferredoxin domain; TIGRFAM: Archaeoflavoprotein MJ0208; PFAM: Flavoprotein; 4Fe-4S binding domain.
       0.490
rps8e
TIGRFAM: Ribosomal protein S8e; HAMAP: Ribosomal protein S8e, archaeal; KEGG: mth:MTH207 30S ribosomal protein S8e; PFAM: Ribosomal protein S8e/ribosomal biogenesis NSA2.
   
    0.455
ADZ10182.1
Small GTP-binding protein; KEGG: mmg:MTBMA_c12550 GTPase; TIGRFAM: Small GTP-binding protein; PFAM: GTP-binding protein, HSR1-related.
   
    0.451
guaAB
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
    0.446
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydromethanopterin (H4MPT) serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro- aldol mechanism; Belongs to the SHMT family.
       0.430
ADZ10196.1
TIGRFAM: Deoxyhypusine synthase; KEGG: mth:MTH127 deoxyhypusine synthase; PFAM: Deoxyhypusine synthase.
  
 
 0.420
ADZ10056.1
Tetratricopeptide TPR_1 repeat-containing protein; KEGG: ter:Tery_3996 tetratricopeptide TPR_2; PFAM: Tetratricopeptide TPR-1; Tetratricopeptide TPR2; SMART: Tetratricopeptide repeat.
 
  
 0.419
ADZ10511.1
PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-1; KEGG: mru:mru_0452 TPR repeat-containing protein.
 
  
 0.418
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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