Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ADZ08415.1PFAM: Protein of unknown function DUF169; KEGG: mth:MTH469 hypothetical protein. (227 aa)    
Predicted Functional Partners:
ADZ10027.1
APHP domain protein; PFAM: APHP; KEGG: mmg:MTBMA_c13780 hypothetical protein.
  
     0.612
ADZ08986.1
KEGG: mmg:MTBMA_c04730 hypothetical protein.
  
     0.516
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydromethanopterin (H4MPT) serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro- aldol mechanism; Belongs to the SHMT family.
       0.515
ADZ08584.1
KEGG: mth:MTH1192 hypothetical protein.
  
     0.479
ADZ08416.1
4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
       0.477
ADZ10132.1
Redox-active disulfide protein 1; KEGG: mmg:MTBMA_c12030 thioredoxin; TIGRFAM: Thioredoxins/glutaredoxin; PFAM: Glutaredoxin.
 
  
 0.476
ADZ10048.1
PFAM: Peptidase C60, sortase A/B; KEGG: mmg:MTBMA_c03990 sortase related protein.
  
     0.461
ADZ08585.1
KEGG: mth:MTH1192 hypothetical protein.
  
     0.459
ADZ08940.1
Methanogenesis marker protein 17; KEGG: mth:MTH1870 hypothetical protein; TIGRFAM: Uncharacterised conserved protein UCP019464, methanogenesis; PFAM: Uncharacterised conserved protein UCP019464, methanogenesis.
  
     0.459
ADZ08937.1
PFAM: Uncharacterised conserved protein UCP006557, signal transduction; KEGG: mfv:Mfer_1093 hypothetical protein.
  
    0.450
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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