Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADZ08431.1PFAM: Radical SAM; KEGG: mmg:MTBMA_c17810 glycyl radical-activating enzyme. (334 aa)    
Predicted Functional Partners:
ADZ09068.1
UPF0103 protein; KEGG: mfv:Mfer_0894 hypothetical protein; HAMAP: Uncharacterised protein family UPF0103; PFAM: UPF0103/Mediator of ErbB2-driven cell motility (Memo-related); Belongs to the MEMO1 family.
     0.962
ADZ10183.1
TIGRFAM: AMMECR1; HAMAP: AMMECR1-domain protein; KEGG: mru:mru_1728 AMMECR1 domain-containing protein; PFAM: AMMECR1.
     0.947
thiL
Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.
       0.862
ADZ10288.1
PFAM: Protein of unknown function DUF98; KEGG: mth:MTH1632 hypothetical protein.
  
    0.736
cbiX
Sirohydrochlorin cobaltochelatase; Catalyzes the insertion of Co(2+) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the insertion of Ni(2+) into sirohydrochlorin to yield Ni- sirohydrochlorin.
  
    0.722
ADZ08434.1
PFAM: Domain of unknown function DUF35, OB-fold, C-terminal; KEGG: mmg:MTBMA_c17840 nucleic acid-binding protein.
     
 0.721
ADZ08662.1
Alcohol dehydrogenase; KEGG: gur:Gura_3532 iron-containing alcohol dehydrogenase; PFAM: Alcohol dehydrogenase, iron-type.
 
  
 0.647
ADZ09975.1
Nitrite reductase (NAD(P)H); KEGG: mba:Mbar_A3664 hypothetical protein; PFAM: Nitrite/sulphite reductase 4Fe-4S domain; Nitrite/sulphite reductase, hemoprotein beta-component, ferrodoxin-like.
  
  
 0.542
ADZ08464.1
KEGG: mmg:MTBMA_c16910 hypothetical protein; TIGRFAM: Conserved hypothetical protein CHP00375; PFAM: PHP, C-terminal.
       0.532
moaA
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family.
  
  
 0.532
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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