STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADZ08453.1UPF0215 protein; Manually curated; HAMAP: Protein of unknown function DUF99; KEGG: mmg:MTBMA_c17020 hypothetical protein; PFAM: Protein of unknown function DUF99; Belongs to the UPF0215 family. (202 aa)    
Predicted Functional Partners:
csl4
RNA-binding domain, S1; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs.
 
     0.902
ADZ08452.1
PFAM: DNA-directed RNA polymerase, dimerisation; KEGG: mth:MTH1317 DNA-dependent RNA polymerase, subunit L.
 
     0.892
ADZ08454.1
PFAM: NUDIX hydrolase domain; KEGG: mst:Msp_1534 putative ADP-ribose pyrophosphatase.
       0.782
ADZ08450.1
Universal diphthamide biosynthesis domain-containing protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family.
       0.533
hpt
Phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.
       0.508
ADZ08455.1
Transcription termination factor Tfs; TIGRFAM: DNA-directed RNA polymerase, subunit M, archaeal; PFAM: Zinc finger, TFIIS-type; DNA-directed RNA polymerase, M/15kDa subunit; KEGG: mst:Msp_1533 RpoM1; SMART: Zinc finger, TFIIS-type; DNA-directed RNA polymerase, M/15kDa subunit; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
       0.479
rps27ae
KEGG: mst:Msp_0620 30S ribosomal protein S27ae; HAMAP: Ribosomal protein S27ae; PFAM: Ribosomal protein S27a; Belongs to the eukaryotic ribosomal protein eS31 family.
 
     0.479
ADZ08834.1
PFAM: Protein of unknown function DUF434; KEGG: mfv:Mfer_0750 hypothetical protein.
 
     0.454
ADZ10595.1
O-phospho-L-seryl-tRNA:Cys-tRNA synthase; Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L- cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)); Belongs to the SepCysS family.
  
     0.434
ADZ10545.1
PFAM: Protein of unknown function DUF211; KEGG: mmg:MTBMA_c12840 hypothetical protein.
  
     0.432
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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