Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADZ08464.1KEGG: mmg:MTBMA_c16910 hypothetical protein; TIGRFAM: Conserved hypothetical protein CHP00375; PFAM: PHP, C-terminal. (387 aa)    
Predicted Functional Partners:
ADZ08463.1
TIGRFAM: Conserved hypothetical protein CHP00062; KEGG: mmg:MTBMA_c16920 hypothetical protein.
       0.823
eif2a
Translation initiation factor 2 subunit alpha; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-alpha family.
       0.753
nop10
Ribosome biogenesis protein Nop10; Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA.
       0.753
ADZ09868.1
PFAM: DNA helicase, UvrD/REP type; KEGG: mmg:MTBMA_c08650 ATP-dependent DNA helicase.
    
 0.742
rpl44e
Ribosomal protein L44E; Binds to the 23S rRNA.
       0.690
rps27e
KEGG: mmg:MTBMA_c16950 30S ribosomal protein S27e; HAMAP: Ribosomal protein S27e, archaea; PFAM: Ribosomal protein S27e.
       0.690
ADZ08465.1
Hypothetical protein.
       0.581
thiL
Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.
       0.541
ADZ09824.1
Cl- channel voltage-gated family protein; PFAM: Chloride channel, voltage gated; KEGG: amr:AM1_2979 Cl-channel, voltage gated.
       0.541
ADZ08431.1
PFAM: Radical SAM; KEGG: mmg:MTBMA_c17810 glycyl radical-activating enzyme.
       0.532
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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