STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADZ08470.1TIGRFAM: Coenzyme F420 hydrogenase, subunit alpha; KEGG: mth:MTH1300 coenzyme F420-reducing hydrogenase, alpha subunit; PFAM: Nickel-dependent hydrogenase, large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (405 aa)    
Predicted Functional Partners:
mtd
F420-dependent methylenetetrahydromethanopterin dehydrogenase; Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT.
  
  
 0.999
ADZ08472.1
TIGRFAM: Coenzyme F420 hydrogenase, subunit gamma; KEGG: mmg:MTBMA_c16840 F420-reducing hydrogenase, subunit gamma; PFAM: NADH:ubiquinone oxidoreductase-like, 20kDa subunit; 4Fe-4S binding domain.
 
 0.999
ADZ08473.1
TIGRFAM: Coenzyme F420 hydrogenase, subunit beta; KEGG: mmg:MTBMA_c16830 F420-reducing hydrogenase, subunit beta; PFAM: Coenzyme F420 hydrogenase/dehydrogenase beta subunit, C-terminal; Coenzyme F420 hydrogenase/dehydrogenase beta subunit, N-terminal.
 
 0.999
ADZ08484.1
Acylphosphatase; TIGRFAM: Carbamoyltransferase, HypF-type; HAMAP: Acylphosphatase; KEGG: mmg:MTBMA_c16720 hydrogenase maturation factor HypF; PFAM: Sua5/YciO/YrdC, N-terminal; Acylphosphatase-like; Zinc finger, HypF-type.
 
 
 
 0.999
ftr
Formylmethanofuran/tetrahydromethanopterin N-formyltransferase; Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) and methanofuran (MFR); Belongs to the FTR family.
      
 0.999
mtrA
Tetrahydromethanopterin S-methyltransferase subunit A; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step; Belongs to the MtrA family.
  
   
 0.999
ADZ09532.1
KEGG: mth:MTH384 hypothetical protein.
      
 0.999
ADZ10415.1
KEGG: mmg:MTBMA_c11780 hydrogenase maturation factor HypB; TIGRFAM: Hydrogenase accessory protein HypB; PFAM: Cobalamin (vitamin B12) biosynthesis CobW-like.
 
  
 0.999
hypA
Hydrogenase nickel incorporation protein hypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
 
 0.999
ADZ08471.1
KEGG: mmg:MTBMA_c16850 F420-reducing hydrogenase, subunit delta; TIGRFAM: Peptidase A31, coenzyme F420-reducing hydrogenase delta subunit; Peptidase A31, hydrogen uptake protein; PFAM: Peptidase A31, hydrogen uptake protein.
 
 0.998
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.