STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADZ08471.1KEGG: mmg:MTBMA_c16850 F420-reducing hydrogenase, subunit delta; TIGRFAM: Peptidase A31, coenzyme F420-reducing hydrogenase delta subunit; Peptidase A31, hydrogen uptake protein; PFAM: Peptidase A31, hydrogen uptake protein. (156 aa)    
Predicted Functional Partners:
ADZ08470.1
TIGRFAM: Coenzyme F420 hydrogenase, subunit alpha; KEGG: mth:MTH1300 coenzyme F420-reducing hydrogenase, alpha subunit; PFAM: Nickel-dependent hydrogenase, large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
 0.998
ADZ08472.1
TIGRFAM: Coenzyme F420 hydrogenase, subunit gamma; KEGG: mmg:MTBMA_c16840 F420-reducing hydrogenase, subunit gamma; PFAM: NADH:ubiquinone oxidoreductase-like, 20kDa subunit; 4Fe-4S binding domain.
 
 
 0.997
ADZ08473.1
TIGRFAM: Coenzyme F420 hydrogenase, subunit beta; KEGG: mmg:MTBMA_c16830 F420-reducing hydrogenase, subunit beta; PFAM: Coenzyme F420 hydrogenase/dehydrogenase beta subunit, C-terminal; Coenzyme F420 hydrogenase/dehydrogenase beta subunit, N-terminal.
 
 
 0.995
ADZ08825.1
Coenzyme F420 hydrogenase; KEGG: mmg:MTBMA_c06440 F420-dependent glutamate synthase; PFAM: Coenzyme F420 hydrogenase/dehydrogenase beta subunit, C-terminal; 4Fe-4S binding domain; Coenzyme F420 hydrogenase/dehydrogenase beta subunit, N-terminal.
  
 
 0.929
mer
5,10-methylenetetrahydromethanopterin reductase; Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT; Belongs to the mer family.
  
 
 0.920
mtd
F420-dependent methylenetetrahydromethanopterin dehydrogenase; Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT.
  
  
 0.916
ADZ09113.1
PFAM: Coenzyme F420 hydrogenase/dehydrogenase beta subunit, C-terminal; Coenzyme F420 hydrogenase/dehydrogenase beta subunit, N-terminal; 4Fe-4S binding domain; KEGG: mth:MTH341 coenzyme F420-reducing hydrogenase, beta subunit-like protein.
     
  0.900
ADZ08484.1
Acylphosphatase; TIGRFAM: Carbamoyltransferase, HypF-type; HAMAP: Acylphosphatase; KEGG: mmg:MTBMA_c16720 hydrogenase maturation factor HypF; PFAM: Sua5/YciO/YrdC, N-terminal; Acylphosphatase-like; Zinc finger, HypF-type.
 
   
 0.692
ileS
Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
   
   0.689
ADZ10477.1
KEGG: mmg:MTBMA_c14600 hydrogenase expression/formation protein HypD; TIGRFAM: Hydrogenase formation HypD protein; PFAM: Hydrogenase formation HypD protein.
 
   
 0.684
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.