STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADZ08483.1Transcriptional regulator, ArsR family; KEGG: mst:Msp_1519 transcriptional regulator; PFAM: HTH transcriptional regulator, ArsR; SMART: HTH transcriptional regulator, ArsR. (154 aa)    
Predicted Functional Partners:
ADZ08813.1
Cell division control protein 6-like protein; Involved in regulation of DNA replication.
 
     0.645
grpE
Protein grpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
 
     0.634
rpl40e
HAMAP: 50S ribosomal protein L40e; KEGG: mmg:MTBMA_c09420 50S ribosomal protein L40E; Belongs to the eukaryotic ribosomal protein eL40 family.
 
     0.620
ADZ08673.1
Mov34/MPN/PAD-1 family protein; PFAM: Mov34/MPN/PAD-1; KEGG: mmg:MTBMA_c13570 hypothetical protein.
  
     0.583
ADZ08363.1
Cell division control protein 6-like protein; Involved in regulation of DNA replication.
 
     0.578
ADZ09264.1
UPF0179 protein; KEGG: mmg:MTBMA_c09890 hypothetical protein; HAMAP: Uncharacterised protein family UPF0179; PFAM: Uncharacterised protein family UPF0179; Belongs to the UPF0179 family.
  
     0.564
dnaK
Chaperone protein dnaK; Acts as a chaperone.
 
     0.550
ADZ08445.1
PFAM: RNA polymerase II, Rpb4; KEGG: mth:MTH1324 hypothetical protein.
  
     0.546
ADZ10405.1
Protein of unknown function DUF54; PFAM: Uncharacterised protein family UPF0201; KEGG: mfv:Mfer_0818 hypothetical protein.
  
     0.528
ADZ08993.1
PFAM: Protein of unknown function DUF2070, membrane; KEGG: mmg:MTBMA_c04800 hypothetical protein.
  
     0.521
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.