Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADZ08495.1TrkA-N domain protein; PFAM: Regulator of K+ conductance, N-terminal; Regulator of K+ conductance, C-terminal; KEGG: mth:MTH1265 trk system potassium uptake protein TrkA. (216 aa)    
Predicted Functional Partners:
ADZ08496.1
KEGG: mmg:MTBMA_c16510 potassium uptake protein TrkH; TIGRFAM: Potassium uptake protein TrkH; PFAM: Cation transporter.
 
 
 0.961
ADZ09281.1
PFAM: Cation transporter; KEGG: mst:Msp_0830 trk-type potassium transport system, membrane protein.
 
 
 0.921
ADZ09944.1
PFAM: Cation/H+ exchanger; KEGG: gfo:GFO_0816 sodium/hydrogen exchanger family protein.
     
 0.830
ADZ10337.1
KEGG: mfv:Mfer_1298 uroporphyrinogen III synthase HEM4; PFAM: Tetrapyrrole biosynthesis, uroporphyrinogen III synthase.
 
    0.631
ADZ09238.1
PFAM: Molybdopterin biosynthesis MoaE; KEGG: mru:mru_1268 molybdenum cofactor biosynthesis protein MoaE.
  
    0.606
aroA-2
Phospho-2-dehydro-3-deoxyheptonate aldolase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.
  
  
 0.578
ADZ08935.1
UPF0288 protein; KEGG: mmg:MTBMA_c04360 peptidyl-prolyl cis-trans isomerase related protein; TIGRFAM: Uncharacterised protein family UPF0288, methanogenesis; HAMAP: Uncharacterised protein family UPF0288, methanogenesis; Belongs to the UPF0288 family.
   
    0.574
ADZ09011.1
TIGRFAM: Pyridoxal phosphate-dependent transferase, archaea; KEGG: msi:Msm_0767 selenocysteine synthase, SelA.
  
  
 0.546
ADZ10595.1
O-phospho-L-seryl-tRNA:Cys-tRNA synthase; Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L- cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)); Belongs to the SepCysS family.
   
    0.538
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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