STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADZ08502.1Phosphodiesterase, MJ0936 family; KEGG: mmg:MTBMA_c16490 phosphodiesterase; TIGRFAM: Phosphodiesterase MJ0936; PFAM: Metallo-dependent phosphatase. (160 aa)    
Predicted Functional Partners:
ADZ09250.1
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
 
 
 0.809
ADZ08355.1
Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
 
  
 0.784
ADZ08503.1
PFAM: Lysylphosphatidylglycerol synthetase/UPF0104; KEGG: mmg:MTBMA_c16480 hypothetical protein.
       0.708
ADZ08781.1
KEGG: mfv:Mfer_0045 mcm family protein; PFAM: DNA-dependent ATPase MCM; SMART: DNA-dependent ATPase MCM; Hedgehog/intein hint, N-terminal; Hedgehog/intein hint domain, C-terminal; Belongs to the MCM family.
       0.692
ADZ08501.1
KEGG: mmg:MTBMA_c12790 glycosyltransferase; TIGRFAM: Conserved hypothetical protein CHP00661; PFAM: Glycosyl transferase, family 2.
  
   0.616
purD
Phosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; TIGRFAM: Phosphoribosylglycinamide synthetase; HAMAP: Phosphoribosylglycinamide synthetase; KEGG: mfv:Mfer_0051 phosphoribosylamine--glycine ligase; Belongs to the GARS family.
  
  
 0.473
ADZ09010.1
Protein of unknown function DUF88; KEGG: mmg:MTBMA_c04840 hypothetical protein; TIGRFAM: Conserved hypothetical protein CHP00288; PFAM: Domain of unknown function DUF88.
 
     0.470
ADZ10597.1
Protein of unknown function DUF88; KEGG: mmg:MTBMA_c04840 hypothetical protein; TIGRFAM: Conserved hypothetical protein CHP00288; PFAM: Domain of unknown function DUF88.
 
     0.450
ADZ09420.1
KEGG: mst:Msp_0490 putative asparagine synthetase; TIGRFAM: Asparagine synthase, glutamine-hydrolyzing; PFAM: Asparagine synthase; Glutamine amidotransferase, class-II.
       0.441
ADZ08988.1
PFAM: GTP-binding protein, HSR1-related; KEGG: mmg:MTBMA_c04750 GTP-binding protein.
  
 
 0.440
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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