Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADZ08532.1PFAM: Transcription regulator, TetR-like, DNA-binding, bacterial/archaeal; KEGG: rci:RCIX1914 TetR family transcriptional regulator. (222 aa)    
Predicted Functional Partners:
ADZ08530.1
Long-chain-fatty-acid--CoA ligase; KEGG: shi:Shel_23800 AMP-forming long-chain acyl-CoA synthetase; PFAM: Male sterility, NAD-binding; AMP-dependent synthetase/ligase.
 
   
 0.748
ADZ08528.1
PFAM: Glucose-methanol-choline oxidoreductase, N-terminal; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; 4Fe-4S binding domain; KEGG: shi:Shel_23820 choline dehydrogenase-like flavoprotein.
 
  
 0.726
ADZ08531.1
PFAM: Polysaccharide pyruvyl transferase; KEGG: shi:Shel_23790 hypothetical protein.
 
   
 0.689
ADZ08529.1
Hypothetical protein; Manually curated.
       0.641
ADZ09616.1
PFAM: Transcription regulator, TetR-like, DNA-binding, bacterial/archaeal; KEGG: mpi:Mpet_1090 TetR family transcriptional regulator.
  
     0.545
ADZ09955.1
PFAM: Transcription regulator, TetR-like, DNA-binding, bacterial/archaeal; KEGG: mvo:Mvol_0570 transcriptional regulator, TetR family.
  
     0.511
ADZ09960.1
Regulatory protein TetR; PFAM: Transcription regulator, TetR-like, DNA-binding, bacterial/archaeal; KEGG: hor:Hore_13530 transcriptional regulator, TetR family.
  
     0.446
ADZ08533.1
PFAM: Amino acid-binding ACT; KEGG: mmg:MTBMA_c16230 energy-converting hydrogenase B, subunit Q.
       0.408
ADZ09961.1
Regulatory protein TetR; PFAM: Transcription regulator, TetR-like, DNA-binding, bacterial/archaeal; KEGG: csc:Csac_2191 TetR family transcriptional regulator.
  
     0.405
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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