STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADZ08543.1PFAM: Protein of unknown function DUF366; KEGG: mst:Msp_1433 hypothetical protein. (194 aa)    
Predicted Functional Partners:
ADZ08544.1
KEGG: mmg:MTBMA_c16130 6-pyruvoyl tetrahydrobiopterin synthase.
 
     0.932
queE
Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
 
     0.899
ADZ08546.1
Putative signal transduction protein with CBS domains; KEGG: mth:MTH1226 inosine-5'-monophosphate dehydrogenase related protein V; PFAM: Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core.
       0.763
ADZ08547.1
Putative signal transduction protein with CBS domains; KEGG: mmg:MTBMA_c16100 CBS domain-containing protein; PFAM: Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core.
       0.752
ADZ08915.1
TIGRFAM: Succinate dehydrogenase/fumarate reductase iron-sulphur protein; KEGG: mmg:MTBMA_c04210 thiol:fumarate reductase, subunit B; PFAM: Cysteine-rich domain; Ferredoxin.
       0.600
ADZ08542.1
PFAM: Domain of unknown function DUF296; KEGG: bba:Bd1709 putative DNA-binding protein.
       0.581
ADZ08541.1
DNA polymerase beta domain protein region; PFAM: Nucleotidyl transferase domain; KEGG: mth:MTH1231 hypothetical protein.
 
     0.525
ADZ08933.1
PFAM: Uncharacterised conserved protein UCP006598; KEGG: mmg:MTBMA_c04340 hypothetical protein.
  
     0.483
mtrC
Tetrahydromethanopterin S-methyltransferase, subunit C; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.
  
     0.474
ADZ08551.1
Y414 protein; KEGG: mfv:Mfer_0241 ATP dependent DNA ligase; TIGRFAM: Uncharacterised protein family MJ0414; PFAM: DNA ligase, ATP-dependent, central.
 
     0.441
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
Server load: medium (58%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.