Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
queERadical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (233 aa)    
Predicted Functional Partners:
ADZ08544.1
KEGG: mmg:MTBMA_c16130 6-pyruvoyl tetrahydrobiopterin synthase.
 
 
 0.999
queC
exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.
 
 
 0.998
ADZ10744.1
TIGRFAM: Ribonucleoside-triphosphate reductase, anaerobic; KEGG: mmg:MTBMA_c01230 anaerobic ribonucleotide-triphosphate reductase; PFAM: ATP-cone.
 
 
 0.970
ADZ08543.1
PFAM: Protein of unknown function DUF366; KEGG: mst:Msp_1433 hypothetical protein.
 
     0.909
ADZ08546.1
Putative signal transduction protein with CBS domains; KEGG: mth:MTH1226 inosine-5'-monophosphate dehydrogenase related protein V; PFAM: Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core.
     
 0.893
ADZ08547.1
Putative signal transduction protein with CBS domains; KEGG: mmg:MTBMA_c16100 CBS domain-containing protein; PFAM: Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core.
     
 0.864
tgtA
7-cyano-7-deazaguanine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family.
 
   
 0.697
ADZ08542.1
PFAM: Domain of unknown function DUF296; KEGG: bba:Bd1709 putative DNA-binding protein.
 
     0.616
moaA
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family.
     
 0.616
ADZ08548.1
Putative signal transduction protein with CBS domains; KEGG: mmg:MTBMA_c16090 CBS domain-containing protein; PFAM: Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core.
     
 0.589
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.