Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADZ08551.1Y414 protein; KEGG: mfv:Mfer_0241 ATP dependent DNA ligase; TIGRFAM: Uncharacterised protein family MJ0414; PFAM: DNA ligase, ATP-dependent, central. (404 aa)    
Predicted Functional Partners:
ADZ08874.1
UPF0278 protein; RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. Belongs to the HARP family.
 
     0.880
ADZ08548.1
Putative signal transduction protein with CBS domains; KEGG: mmg:MTBMA_c16090 CBS domain-containing protein; PFAM: Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core.
 
     0.782
ADZ08549.1
Putative signal transduction protein with CBS domains; KEGG: mth:MTH1223 inosine-5'-monophosphate dehydrogenase related protein II; PFAM: Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core.
 
     0.735
ADZ08550.1
CBS domain containing membrane protein; KEGG: mth:MTH1222 inosine-5'-monophosphate dehydrogenase related protein I; PFAM: Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core.
       0.731
ADZ08552.1
KEGG: mmg:MTBMA_c16050 prephenate dehydratase; PFAM: Prephenate dehydratase; Amino acid-binding ACT.
       0.714
ADZ08547.1
Putative signal transduction protein with CBS domains; KEGG: mmg:MTBMA_c16100 CBS domain-containing protein; PFAM: Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core.
 
     0.707
ADZ08546.1
Putative signal transduction protein with CBS domains; KEGG: mth:MTH1226 inosine-5'-monophosphate dehydrogenase related protein V; PFAM: Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core.
       0.663
ADZ10082.1
PFAM: Protein of unknown function DUF166; KEGG: mth:MTH1356 hypothetical protein.
 
     0.663
ADZ08694.1
Protein of unknown function DUF61; PFAM: Uncharacterised protein family UPF0216; KEGG: mth:MTH949 hypothetical protein; Belongs to the UPF0216 family.
  
     0.638
ADZ08885.1
PFAM: Glutamate synthase, alpha subunit, C-terminal; KEGG: mfv:Mfer_0106 glutamate synthase alpha subunit domain protein.
  
     0.616
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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