Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADZ08570.1TIGRFAM: Sulfopyruvate decarboxylase, beta subunit; KEGG: mmg:MTBMA_c15850 sulfopyruvate decarboxylase, beta subunit; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding. (182 aa)    
Predicted Functional Partners:
ADZ08571.1
KEGG: msi:Msm_0080 sulfopyruvate decarboxylase, ComD; TIGRFAM: Sulfopyruvate decarboxylase, alpha subunit.
  
 0.999
ADZ08572.1
Malate dehydrogenase (NADP(+)); KEGG: mmg:MTBMA_c15830 sulfolactate dehydrogenase; PFAM: Malate/L-lactate dehydrogenase.
    
 0.990
ADZ08603.1
KEGG: mmg:MTBMA_c15500 methyl-coenzyme M reductase I, subunit epsilon; TIGRFAM: Methyl-coenzyme M reductase, protein C; PFAM: Methyl-coenzyme M reductase, protein C.
      
 0.682
ADZ08472.1
TIGRFAM: Coenzyme F420 hydrogenase, subunit gamma; KEGG: mmg:MTBMA_c16840 F420-reducing hydrogenase, subunit gamma; PFAM: NADH:ubiquinone oxidoreductase-like, 20kDa subunit; 4Fe-4S binding domain.
  
   
 0.678
ADZ10365.1
PFAM: Protein of unknown function DUF1802; KEGG: mth:MTH1210 mrr restriction system related protein.
   
    0.649
mtrA
Tetrahydromethanopterin S-methyltransferase subunit A; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step; Belongs to the MtrA family.
      
 0.635
purM
TIGRFAM: Phosphoribosylformylglycinamidine cyclo-ligase; KEGG: msi:Msm_1039 phosphoribosylaminoimidazole synthetase; PFAM: AIR synthase-related protein; AIR synthase-related protein, C-terminal.
       0.608
ADZ09698.1
Transcriptional regulator, TrmB; PFAM: Transcription regulator TrmB, N-terminal; KEGG: mmg:MTBMA_c00400 transcriptional regulator.
  
    0.596
ADZ10360.1
Transcriptional regulator, TrmB; KEGG: mth:MTH1454 hypothetical protein; manually curated; PFAM: Transcription regulator TrmB, N-terminal.
  
    0.596
ADZ10458.1
TIGRFAM: Phosphosulpholactate synthase; KEGG: mth:MTH1674 hypothetical protein; PFAM: (2R)-phospho-3-sulpholactate synthase, ComA.
  
  
 0.584
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.